A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins
Bone Development -- genetics : Cartilage and bone development and its disorders / 4th ESPE Advanced Seminar in Developmental Endocrinology, Stockholm, June 30-July 1, 2010 ; volume editors, Cecilia Camacho-Hübner, Ola Nilsson, Lars Sävendahl
Bone Development -- physiology -- Congresses : Nutritional Influences on Bone Health : 10th International Symposium / Connie M. Weaver, Heike Bischoff-Ferrari, Robin M. Daly, Man-Sau Wong, editors
Bone Diseases, Endocrine : Cartilage and bone development and its disorders / 4th ESPE Advanced Seminar in Developmental Endocrinology, Stockholm, June 30-July 1, 2010 ; volume editors, Cecilia Camacho-Hübner, Ola Nilsson, Lars Sävendahl
Bone diseases in children -- Congresses : Cartilage and bone development and its disorders / 4th ESPE Advanced Seminar in Developmental Endocrinology, Stockholm, June 30-July 1, 2010 ; volume editors, Cecilia Camacho-Hübner, Ola Nilsson, Lars Sävendahl
Bone Diseases -- metabolism : Nutritional influences on bone health / Peter Burckhardt, Bess Dawson-Hughes, Connie Weaver, editors
2010
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Bone Diseases -- nursing. : The skeletal system and the muscular system / edited by Janet T.E. Riddle ; with contributions from Kathleen B. Nicoll, Isabella I. Rowantree