Age-Related Changes in Whole-Bone Structure and Strength / Matthew J. Silva and Karl J. Jepsen -- Characterisation of Trabecular Bone Structure / Ian H. Parkinson and Nicola L. Fazzalari -- Cortical Bone Mechanics and Composition: Effects of Age and Gender / Xiaodu Wang -- Bone Microdamage and Its Contributions to Fracture / Lamya Karim and Deepak Vashishth -- Changes in Cortical Bone Mineral and Microstructure with Aging and Osteoporosis / Janardhan Yerramshetty and Ozan Akkus -- Factor of Risk for Fracture / Dennis E. Anderson and Mary L. Bouxsein -- Bisphosphonates and PTH for Preventing Fractures / David B. Burr and Matthew R. Allen -- Bone Cell Mechanoresponsiveness / Damian C. Genetos and Christopher R. Jacobs -- The Effect of Aging on Skeletal Mechanoresponsiveness: Animal Studies / Akhilesh A. Kotiya and Matthew J. Silva -- Skeletal Mechanoresponsiveness: Effects of Sex Hormones / Katherine M. Melville, Natalie H. Kelly and Marjolein C.H. van der Meulen -- Effects of Exercise and Physical Interventions on Bone: Clinical Studies / Wendy M. Kohrt, Karen L. Villalon and Daniel W. Barry
Summary
The focus of this book is on mechanical aspects of skeletal fragility related to aging and osteoporosis. Topics include: Age-related changes in trabecular structure and strength; age-related changes in cortical material properties; age-related changes in whole-bone structure; predicting bone strength and fracture risk using image-based methods and finite element analysis; animal models of osteoporosis and aging; age-related changes in skeletal mechano responsiveness; exercise and physical interventions for osteoporosis
