| Description |
1 online resource (xiii, 391 pages) : illustrations (some color) |
| Series |
Neuromethods, 1940-6045 ; 77 |
|
Springer protocols |
|
Neuromethods ; 77.
|
|
Springer protocols (Series)
|
| Contents |
Brain tumor models to predict clinical outcome : like the Phoenix? / Lois A. Lampson -- Animal models in cancer research : assessment of severity and the application of humane endpoints / Jose M. Orellana-Muriana -- VM mouse model of glioblastoma multiforme / Thomas N. Seyfried, Laura M. Shelton, and Leanne C. Huysentruyt -- Oligodendroglioma model / Nanna Lindberg and Lene Uhrbom -- Medulloblastoma model / Jasmine Lau and William A. Weiss -- Learning about retinoblastoma from mouse models that missed / David Cobrinik -- Ependymoma models / Jesus Vaquero and Mercedes Zurita -- Meningioma models / Jessica Rainey and Randy L. Jensen -- Pituitary models / Walavan Sivakumar and William T. Couldwell -- Growth regulation of nervous system tumors : models for assessment of angiogenesis in brain tumors / Kelly Burrell [and others] -- Using genetically-engineered mouse models to understand low-grade glioma development and growth in children / Aparna Kaul, Ibrahim Hussain, and David H. Gutmann -- EGFR and tumor-suppressor function in brain cancer development / Julie Lessard and Al Charest -- Rodent glioma models : intracranial stereotactic allografts and xenografts / Hikmat Assi [and others] -- Immunotherapy of high-grade gliomas : preclinical in vivo experiments in animal models / Kristen A. Batich, Bryan D. Choi, and Duane A. Mitchell -- Assessing mechanisms of glioblastoma invasion / Stephen M. Robbins and Donna L. Senger -- Positron emission tomography (PET)-based molecular imaging / Yannic Waerzeggers [and others] -- In vivo magnetic resonance spectroscopic imaging (MRSI) and ex vivo quantitative neuropathology by high resolution magic angle spinning proton magnetic resonance spectroscopy (HRMAS) / Rui V. Simoes [and others] -- Single photon emission computed tomography (SPECT) in small animal CNS research / Andre Constantinesco, Christian Goetz, and Philippe Choquet |
| Summary |
Although the available models, whether at the cellular, tissue, or animal level, do not exactly represent the biology of human brain tumors, animal models can offer significant insights into these tumors, providing a better understanding of biological mechanisms underlying tumor generation, growth, angiogenesis, invasion, and metastasis. Animal Models of Brain Tumors brings together developments and discoveries in "in vivo" experimental tumor research that have provided advances in our understanding of the cellular and molecular mechanisms involved in the generation, progression, and clinical outcome of brain neoplasms. Broken into convenient sections, this thorough volume includes topics such as animal model insights into human brain neoplasms, the cellular, molecular, and genetic basis of brain tumors, therapies in the treatment of malignant glioma, as well as imaging technologies in animal tumor models, i.e. measuring brain tumor growth and metabolism. Written for the popular Neuromethods series, chapters include the kind of detailed description and implementation advice that is essential for achieving successful results. Authoritative and cutting-edge, Animal Models of Brain Tumors provides the key methods needed to validate, compare, and contrast the animal model with its proposed human counterpart and further the understanding of our own serious ailments |
| Analysis |
biomedische wetenschappen |
|
biomedicine |
|
neurologie |
|
neurology |
|
neurowetenschap |
|
neuroscience |
|
diermodellen |
|
animal models |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Brain -- Tumors -- Animal models
|
|
Diseases -- Animal models.
|
|
Animals
|
|
Brain Neoplasms
|
|
Disease Models, Animal
|
|
Diseases -- Animal models
|
| Genre/Form |
Laboratory manuals.
|
|
Manuels de laboratoire.
|
| Form |
Electronic book
|
| Author |
Murillo, Ricardo Martinez
|
|
Martinez, Alfredo
|
| ISBN |
9781627032094 |
|
1627032096 |
|
