Identification and characterization of neural progenitor cells in the adult mammalian brain / Sara Gil-Perotín, Arturo Álvarez-Buylla and José Manuel Garcia-Verdugo
Historic overview -- Research methodologies for adult neurogenesis -- Neurogenesis in the intact adult mammalian central nervous system -- Oncogenesis vs neurogenesis -- Adult neurogenesis under pathological stimulation : ischemia -- Therapeutic potential of neural stem cells
Summary
Adult neurogenesis has been questioned for many years. In the early 1900s, a dogma was established that denied new neuron formation in the adult brain. Adult neural stem cells are undifferentiated cells that are present in the adult brain and are capable of dividing and differentiating into glia and new neurons