Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible
Cancer -- Susceptibility -- Research -- Case studies. : Engaging patients to understand their family history for cancer : a case study about recruiting in a safety-net women's clinic / Vivian M. Rodríguez, Maria E. Gyure, John M. Quillin, Alex H. Krist, Monika S. Markowitz, Donna McClish, Joann N. Bodurtha
2017
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Cancer -- Sweden. : Cancer-- causes and prevention / Swedish Cancer Committee
The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance
The condition of a pattern of malignancies within a family, but not every individual's necessarily having the same neoplasm. Characteristically the tumor tends to occur at an earlier than average age, individuals may have more than one primary tumor, the tumors may be multicentric, usually more than 25 percent of the individuals in direct lineal descent from the proband are affected, and the cancer predisposition in these families behaves as an autosomal dominant trait with about 60 percent penetrance
Cancer -- Thérapeutique -- Informatique. : Cancer informatics in the post genomic era : toward information-based medicine / edited by Igor Jurisica, Dennis A. Wigle, Bill Wong
2007
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Cancer -- Thérapeutique -- Recherche. : Cancer microenvironment and therapeutic implications : tumor pathophysiology mechanisms and therapeutic strategies / edited by Gianfranco Baronzio, Gianmaria Fiorentini Christopher R. Cogle
