Cancer morphology, carcinogenesis and genetic instability: a background; Abnormalities of chromatin in tumor cells; Aneuploidy, stem cells and cancer; The mode of action of organic carcinogens on cellular structures; Metal ions and carcinogenesis; Actions of ultraviolet light on cellular structures; Actions of radiation on living cells in the "post-bystander" era; Viral carcinogenesis and genomic instability; Abnormalities of cell structures in tumors: apoptosis in tumors; Molecular regulation of tumor angiogenesis: mechanisms and therapeutic implications
Summary
Presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells. This book includes reviews of cellular targets of known carcinogens, and presents varying viewpoints of how morphological abnormalities and the actions of carcinogens might be related