Title Cell cycle regulation / Philipp Kaldis (ed.)

Published Berlin : Springer, 2006

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Description 1 online resource (xii, 374 pages) : illustrations Series Results and problems in cell differentiation ; 42 Results and problems in cell differentiation ; 42 Contents G1 phase : components, conundrums, context / Stephanie J. Moeller and Robert J. Sheaff -- Regulation of S phase / Jamie K. Teer and Anindya Dutta -- Checkpoint and coordinated cellular responses to DNA damage / Xiaohong H. Yang and Lee Zou -- Protein kinases involved in mitotic spindle checkpoint regulation / Ingrid Hoffmann -- The centrosome cycle / Christopher P. Mattison and Mark Winey -- The ubiquitin-proteasome pathway in cell cycle control / Steven I. Reed -- The retinoblastoma gene family in cell cycle regulation and suppression of tumorigenesis / Jan-Hermen Dannenberg and Hein P.J. te Riele -- Modeling cell cycle control and cancer with pRB tumor suppressor / Lili Yamasaki -- Senescence and cell cycle control / Hiroaki Kiyokawa -- Mouse models of cell cycle regulators : new paradigms / Eiman Aleem and Philipp Kaldis -- Control of cell proliferation and growth by Myc proteins / Sandra Bernard and Martin Eilers -- Cell cycle regulation in mammalian germ cells / Changanamkandath Rajesh and Douglas L. Pittman Summary The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer Analysis biochemie biochemistry neoplasms celbiologie cellular biology Cellular Biology Celbiologie Bibliography Includes bibliographical references and index Notes Print version record In Springer e-books Subject Cellular control mechanisms. Cell cycle -- Regulation. Cell cycle. Tumor proteins. Cell physiology. Proteins. Growth. Tumor suppressor proteins. Cell Cycle Cell Cycle Proteins Neoplasm Proteins Cell Physiological Phenomena Proteins Cell Growth Processes Amino Acids, Peptides, and Proteins Growth Growth and Development Chemicals and Drugs Phenomena and Processes Physiological Phenomena Cell Cycle Proteins -- physiology Cell Proliferation Tumor Suppressor Proteins protein. growth. Cellular control mechanisms. Cell cycle -- Regulation. Cell cycle. Cell Cycle Proteins -- physiology. Cell proliferation. Tumor Suppressor Proteins. Biomédecine. Sciences de la vie. Cell cycle -- Regulation. Cellular control mechanisms. Form Electronic book Author Kaldis, Philipp ISBN 9783540345534 3540345531 9783540345527 3540345523

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