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Title Advances in nuclear architecture / Niall M. Adams, Paul S. Freemont, editors
Published Dordrecht ; New York : Springer, ©2011


Description 1 online resource (vii, 210 pages) : illustrations (some color)
Contents Advances in Nuclear Architecture; Foreword; Contents; Chapter 1: Nuclear Subdomains and Cancer; Chapter 2: Spatial Point Process Analysis of Promyelocytic Leukemia Nuclear Bodies; Chapter 3: Quantitative Approaches to Nuclear Architecture Analysis and Modelling; Chapter 4: Statistical Shape Theory and Registration Methods for Analyzing the 3D Architecture of Chromatin in Interphase Cell Nuclei; Chapter 5: Nuclear Molecular Motors for Active, Directed Chromatin Movement in Interphase Nuclei; Chapter 6: Methodology for Quantitative Analysis of 3-D Nuclear Architecture
Summary This book provides a snapshot of the state-of-the art in the study of mammalian cell nuclear architecture, and features a diverse range of chapters written by top researchers. A key aspect is an emphasis on precise and repeatable quantitative analysis and simulation in addition to the more familiar biological perspective. The fusion of such material frames the future of the discipline. Quantitative contributions stress reproducible and robust 3D analysis, using a variety of tools ranging from point pattern analysis to shape registration methods. Biological insights include the role of nuclear
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cytology.
Cell Nucleus -- ultrastructure
Cell Biology
SCIENCE -- Life Sciences -- Cell Biology.
Form Electronic book
Author Adams, Niall M., 1968-
Freemont, Paul S.
LC no. 2010937564
ISBN 9789048198993