| Description |
viii, 262 pages : illustrations ; 26 cm |
| Contents |
1. Introduction, the significance of radiobiology for radiotherapy. 2. Cell proliferation and growth rate of tumours. -- 3. Proliferative and cellular organization of normal tissues. -- 4. Radiation response and tolerance of normal tissues. -- 5. Volume effects in normal tissues. -- 6. Cell survival as a determinant of tumour response. -- 7. Models of radiation cell killing. -- 8. DNA damage and cell killing. -- 9. Genetic control of the cellular response to ionizing radiation. -- 10. Dose-response relationships in radiotherapy. -- 11. Clinical manifestations of normal-tissue damage. -- 12. Time-dose relationships, the linear-quadatic approach. -- 13. The linear-quadratic model in clinical practice. -- 14 Modified fractionation. -- 15. The oxygen effect and tumour microenvironment. -- 16. Overcoming tumour radioresistance resulting from hypoxia. -- 17. The radiobiology of tumours. -- 18. The dose rate effect, brachytherapy and targeted radiotherapy. -- 19 Particle beams in radiotherapy. -- 20 The combination of radiotherapy and chemotherapy. -- 21 Retreatment tolerance of normal tissues. -- 22. Individualization of therapy |
| Bibliography |
Includes bibliographical references and index |
| Subject |
Radiotherapy.
|
|
Radiobiology.
|
|
Neoplasms -- radiotherapy.
|
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Cell Survival -- radiation effects.
|
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Dose-Response Relationship, Radiation.
|
| Author |
Steel, G. Gordon (George Gordon)
|
| LC no. |
2003267013 |
| ISBN |
0340807830 |
|
