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Title Cell cycle regulation / Philipp Kaldis (ed.)
Published Berlin : Springer, 2006


Description 1 online resource (xii, 374 pages) : illustrations
Series Results and problems in cell differentiation ; 42
Results and problems in cell differentiation ; 42.
Contents G1 phase : components, conundrums, context / Stephanie J. Moeller and Robert J. Sheaff -- Regulation of S phase / Jamie K. Teer and Anindya Dutta -- Checkpoint and coordinated cellular responses to DNA damage / Xiaohong H. Yang and Lee Zou -- Protein kinases involved in mitotic spindle checkpoint regulation / Ingrid Hoffmann -- The centrosome cycle / Christopher P. Mattison and Mark Winey -- The ubiquitin-proteasome pathway in cell cycle control / Steven I. Reed -- The retinoblastoma gene family in cell cycle regulation and suppression of tumorigenesis / Jan-Hermen Dannenberg and Hein P.J. te Riele -- Modeling cell cycle control and cancer with pRB tumor suppressor / Lili Yamasaki -- Senescence and cell cycle control / Hiroaki Kiyokawa -- Mouse models of cell cycle regulators : new paradigms / Eiman Aleem and Philipp Kaldis -- Control of cell proliferation and growth by Myc proteins / Sandra Bernard and Martin Eilers -- Cell cycle regulation in mammalian germ cells / Changanamkandath Rajesh and Douglas L. Pittman
Summary The cell cycle is tightly regulated on many different levels to ensure properly controlled proliferation. Deregulation of cell cycle regulation is a hallmark of cancer. In this book, many aspects of cell cycle regulation are discussed, which include G1, S, M phase control, ubiquitin-mediated degradation, DNA damage response, mitotic spindle checkpoint, the centrosome cycle, Retinoblastoma protein family, the Myc oncogene, and mouse models for tumor suppressors, cyclin-dependent kinases, and meiosis. These chapters written by experts provide an updated view on how the cell cycle is regulated in vivo and about the involvement of cell cycle regulators in cancer
Analysis biochemie
cellular biology
Cellular Biology
Bibliography Includes bibliographical references and index
Notes Print version record
In Springer e-books
Subject Cellular control mechanisms.
Cell cycle -- Regulation.
Cell cycle.
Tumor proteins.
Cell physiology.
Tumor suppressor proteins.
Cell Cycle
Cell Cycle Proteins
Neoplasm Proteins
Cell Physiological Phenomena
Cell Growth Processes
Amino Acids, Peptides, and Proteins
Growth and Development
Chemicals and Drugs
Phenomena and Processes
Physiological Phenomena
Cell Cycle Proteins -- physiology
Cell Proliferation
Tumor Suppressor Proteins
Cellular control mechanisms.
Cell cycle -- Regulation.
Cell cycle.
Cell Cycle Proteins -- physiology.
Cell proliferation.
Tumor Suppressor Proteins.
Sciences de la vie.
Tumor suppressor proteins
Tumor proteins
Cell physiology
Cell cycle
Cell cycle -- Regulation
Cellular control mechanisms
Form Electronic book
Author Kaldis, Philipp
ISBN 9783540345534