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Title Advances in stem cell aging / volume editor, Karl Lenhard Rudolph
Published Basel : Karger, ©2012

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Description 1 online resource
Series Else Kröner-Fresenius symposia, 1663-0114 ; vol. 3
Else Kröner-Fresenius symposia ; v. 3. ;. 1663-0114
Contents Speakers at the symposium / Morita, M. -- Aging of the niche and the microenvironment and its role in stem cell aging / Geiger, H. -- Hematopoietic stem cell aging and cancer / Chen, Y., Ju, Z. -- DNA damage, checkpoint responses, and cell cycle control in aging stem cells / Kleinhans, K.N., Burkhalter, M.D. -- Hematopoietic stem cell aging and fate decision / Illing, A., Morita, Y. -- Stem cell therapy and stress response in pancreas and intestine -- Sperka, T., Omrani, O. -- Niche-stem cell interations and environmental influences / Tang, D. -- Stem cells and metabolism / Missios, P., Guachalla, L. -- Molecular mechanisms of muscle stem cell aging / Baig, A.H., Tümpel, S. -- Neural stem cells in development and aging / Schmidt-Strassburger, U
Summary Adult stem cells are present in most postnatal tissues of mammals. Tissues with high rates of cell turnover depend on the functional capacity of stem cells for lifelong maintenance of tissue homeostasis. Adult stem cells are also required for the regeneration of tissues in response to injury as in, for example, the regeneration of skeletal muscle. In addition to its function in tissue homeostasis and regeneration, adult stem cells can represent the cell type of origin of various types of cancers including leukemia and colorectal cancer. Stem cells are the most long-lived cells in the proliferative compartment of mammalian tissues. Therefore, stem cells have an increased risk of acquiring mutations that could ultimately lead to the transformation of tissue stem cells. This publication presents the current knowledge in the field of stem cell aging, which was discussed at the Else Kröner-Fresenius Symposium on Advances in Stem Cell Aging in 2011. It will be of special interest to scientists working on stem cell research, aging, regeneration, and cancer as well as physicians and scientists specializing in geriatric medicine, internal medicine, and surgery
Bibliography Includes bibliographical references and indexes
Notes Print version record
Subject Stem cells -- Congresses
Cells -- Aging -- Congresses
Cells -- Aging.
DNA damage.
Telomere.
Adult Stem Cells
Cellular Senescence
DNA Damage
Telomere
MEDICAL -- Research.
Telomere
DNA damage
Cells -- Aging
Stem cells
Genre/Form Electronic books
proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congrès.
Form Electronic book
Author Rudolph, K. Lenhard
ISBN 9783318021714
3318021717
9783318021707
3318021709