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Title Interleukin-2 and killer cells in cancer / editor, Eva Lotzová ; associate editor, Ronald B. Herberman
Published Boca Raton, FL : CRC Press, 2018

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Description 1 online resource
Series CRC revivals
CRC revivals
Contents Cover; Title Page; Copyright Page; Preface; The Editor; Associate Editor; Dedication; Contributors; Table of Contents; Chapter 1 Cellular Immunotherapy of Cancer: Preclinical and Clinical Testing UtilizingInter leukin-2; Chapter 2 Long-Term Culture of IL-2 Generated Killer Cells with Antitumor Activity; Chapter 3 Function of Interleukin-2 Activated NK Cells in Leukemia Resistance and Treatment; Chapter 4 Utilizing Lymphokine-Activated Killer Cells for Bone Marrow Purging; Chapter 5 Cell-Mediated Cytotoxicity Against Fresh Solid Tumor Cells: Regulation by Soluble Mediators
Chapter 6 Down-Regulation of Human Bone Marrow Cells and Their Progenitors by IL-2-Activated LymphocytesChapter 7 IL-2-Induced Cytotoxic Cells from Human Thymocytes; Chapter 8 Regulation of NK Cytotoxicity In Vivo in Patients Receiving IL-2; Chapter 9 Synergism between Cyclophosphamide and Interleukin-2; Chapter 10 Human Tumor-Infiltrating Lymphocytes and Their Characterization; Chapter 11 Growth Kinetics, Function, and Characterization of Lymphocytes Infiltrating Ovarian Tumors
Chapter 12 Cancer Treatment Using IL-2-Activated Killer Cells and/or IL-2 in Combination with Chemotherapeutic DrugsChapter 13 Development of Adoptive Immunotherapy with In Vitro Sensitized T Lymphocytes from Mice Bearing Progressively Growing Tumors; Chapter 14 Adoptive Transfer of T Cells for Therapy of Disseminated Leukemia: Antigen Specificity and Function of Tumor-Reactive T Cells; Chapter 15 LAK Cells and Autologous Bone Marrow Transplantation: Toward a Cure for Leukemia
Chapter 16 Tumor Inhibitory Effects of Regional Interleukin-2 Administration and the Role of Lymphokine-Activated Killer CellsChapter 17 Tissue Distribution and Localization of IL-2-Activated Killer Cells after Adoptive Transfer In Vivo; Chapter 18 In Vivo Tissue Distribution of Interleukin-2-Activated Cells; Chapter 19 Role of rIL-2 in Host Resistance Against Cryptococcal Infection; Chapter 20 Role of IL-2 in Growth and Differentiation of Cryptotoxic Cells; Chapter 21 The Interleukin-2 Receptor Complex and Its Role in the Induction of Nonspecific Cytotoxicity
Chapter 22 Regulation of Phosphorylation and Gene Expression in Cytotoxic Lymphocytes by Interleukin-2Chapter 23 Role of the Interleukin-2 Receptor in the Growth and Regulation of LAK Activity; Chapter 24 Surface Structures Involved in Tumor Cell Recognition by Fresh and IL-2-Activated Natural Killer Cells; Index
Summary This is the first-and only-publication available which provides the most recent information in this particular field of biomedicine. Interleukin-2 (IL-2) and IL-2 activated killer cells have been shown to have a potential in the treatment of a variety of human malignant diseases. This work comprehensively summarizes basic aspects of IL-2 as well as its clinical application, therefore making all these aspects easily accessible to the readers. Because of the clinical significance of this molecule in the treatment of cancer, the basic and clinical investigations in the IL-2 field are rapidly expanding, together with the interest of the scientific and medical community. This book is an excellent educational and teaching tool for scientists, clinicians, and students. Those who already have expertise in research in the IL-2 area will find this reference indispensible
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (EBSCO, viewed February 26, 2018)
Subject Cancer -- Immunotherapy.
Killer cells.
Interleukin-2 -- Therapeutic use
Interleukin-2 -- therapeutic use
Killer Cells, Natural -- immunology
Neoplasms -- therapy
HEALTH & FITNESS -- Diseases -- General.
MEDICAL -- Clinical Medicine.
MEDICAL -- Diseases.
MEDICAL -- Evidence-Based Medicine.
MEDICAL -- Internal Medicine.
Cancer -- Immunotherapy
Interleukin-2 -- Therapeutic use
Killer cells
Interleukines -- usage thérapeutique.
Cellules tueuses -- immunologie.
Tumeurs -- Thérapeutique.
Krebs Medizin
Interleukine
Killerzelle
Aufsatzsammlung
Form Electronic book
Author Lotzová, Eva, 1936- editor
Herberman, Ronald B., 1940-
ISBN 9781351082242
1351082248
9781351073790
1351073796
9781351099141
1351099140
9781351090698
1351090690