Limit search to available items
Record 8 of 16
Previous Record Next Record
Book Cover

Title Drug delivery to the central nervous system / edited by Kewal K. Jain
Published New York, N.Y. : Humana Press, ©2010


Description 1 online resource (xii, 321 pages) : illustrations (some color)
Series Springer protocols
Neuromethods, 1940-6045 ; 45
Springer protocols (Series)
Neuromethods ; 45.
Contents An overview of drug delivery to the CNS / K.K. Jain -- Receptor-mediated transport of drugs across the BBB / J.-M. Feng, P.C.W. Lui and J.Y. Li -- Disruption of blood-brain barrier by focused ultrasound for targeted drug delivery to the brain / N. Vykhodtseva -- Prediction of blood-brain barrier penetration by drugs / K. Lanevskij [and others] -- Intraparenchymal delivery and its discontents / R. Raghavan -- Intrathecal drug delivery by implanted pumps / S. Belverud, A. Mogilner and M. Schulder -- Intracarotid drug delivery: Revisiting the past or looking into the future / S. Joshi -- Vesicular systems for intranasal drug delivery / I.A. Alsarra [and others] -- Convection-enhanced drug delivery and monitoring in a rat model / Y. Mardor and Z. Ram -- Intrathecal delivery of stem cells to the spinal cord / B. Neuhuber and I. Fischer -- CNS delivery of peptides across the BBB using the dual-artery in situ brain perfusion model / K.A. Witt [and others] -- An engineered peptide compound platform technology incorporating angiopep for crossing the BBB / R. Gabathuler -- Adeno-associated virus mediated gene therapy in ischemic stroke / Y. Wang, F. Yuan and G.-Y. Yang -- Use of mesenchymal stem cells for gene delivery to intracranial glioma / S.-S. Jeun [and others] -- Convection-enhanced drug delivery to the brain / D. Ding [and others]
Summary Playing an important role in the treatment of neurological disorders, the delivery of drugs to central nervous system (CNS), both administered directly and administered systematically for targeted action, encounters a major challenge in the form of the blood-brain barrier (BBB), which limits the access of drugs to the brain substance. In Drug Delivery to the Central Nervous System, experts in the field present essential methods used to deliver therapeutics across the BBB, both in experimental animals and in humans. In addition to those methods, several overviews of innovative methods and their applications are presented in order to give a glimpse of the future of this research. As a volume in the successful Neuromethods series, this book presents its protocols with the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Drug Delivery to the Central Nervous System serves as an ideal guide to scientists continuing to pursue knowledge of the delicate interactions between pharmaceuticals and the brain
Analysis neurochemie
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Drug delivery systems.
Central nervous system -- Diseases -- Chemotherapy
Drug Delivery Systems -- methods
Drug Delivery Systems
Central Nervous System Diseases -- drug therapy
Central nervous system -- Diseases -- Chemotherapy
Drug delivery systems
Genre/Form Laboratory manuals.
Manuels de laboratoire.
Form Electronic book
Author Jain, K. K. (Kewal K.)
ISBN 9781607615293