| Description |
1 online resource |
| Contents |
Front Cover; Central Serous Chorioretinopathy; Copyright; Dedication; Contents; Contributors; Author Biography; Foreword; Preface; History of Central Serous Choroidopathy (CSC); Section I: Basics; Chapter 1: Pathophysiology of CSCR; Introduction; Mechanisms of Choroidal Changes: Pachychoroid; Retinal Pigment Epithelium (RPE); Neuroretinal Changes; Original Site of the Disease; The Genetic Hypothesis; The Mineralocorticoid Pathway Hypothesis; What are the Consequences of MR Pathway Activation in the RPE/Choroid?; What is the Evidence That MR Pathway is Activated in CSCR?; Conclusions |
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Chapter 4: CSCR Classification and Its FallaciesReferences; Chapter 5: Risk Factors; Gender and Age; Ethnicity; Cardiovascular Diseases and Hypertension; Sympathetic-Parasympathetic Activity and Reactivity; Glucocorticoids; Endocrine Changes; Psychopathology; Gastroesophageal Disorders; Medications Other Than Steroids; Sleep Disturbances; Shift Work and Circadian Disturbances; Other Ocular Conditions; Consequences for Clinical Practice; References; Chapter 6: Genetics; Introduction; Familial CSC-The Basis of a Genetic Component for CSC; A Brief History of Human Genetics; Inheritance Patterns |
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Modern Genotyping MethodsGenetics Studies on CSC; Candidate Gene Studies; Cfh; Cdh5; Pai-1; ARMS2 and Other AMD-Associated Genes; Sgk-1; C4b; Gtsm1; NR3C1 and NR3C2; Genome-Wide Association Analysis; The Genetics of CSC Endophenotypes; Candidate Gene Studies; Genome-Wide Association Study; Discussion; The Role of CFH in CSC; The Complement System; Adrenomedullin; Unanswered Questions-Future Studies; Conclusion; References; Section II: Imaging; Chapter 7: Fundus Autofluorescence; Introduction; FAF Patterns; Acute CSC; Chronic CSC; Role of Widefield FAF; FAF Lifetime; References |
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Chapter 8: Fundus Fluorescein AngiographyInkblot Pattern; Smokestack Pattern; Evolution of Typical Leakage; The Significance of Leakage Intensity on Fluorescein Angiography; Chronic Central Serous Chorioretinopathy; Manifestation of Previous Episodes on Fluorescein Angiography; Fluorescein Angiography Compared to Other Imaging Modalities (Fig. 6); Fundus Autofluorescence; Indocyanine Green Angiography; Optical Coherence Tomography; The Use of Fluorescein Angiography in Choroidal Neovascularization |
| Summary |
Central Serous Chorioretinopathy discusses the mechanisms, pathogenesis and risk factors of CSCR, findings on various imaging modalities, available treatment options, and translational research into new treatment options for CSCR management. This comprehensive book is written for retina specialists and surgeons, researchers and clinical practitioners in sensory systems (vision), and ophthalmologists. Central Serous Chorioretinopathy (CSCR) is a common disorder across the world with a variable prognosis without any standard of care. Recently, advancements in imaging have led to a better understanding of the pathogenesis and mechanisms of this disease |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Online resource; title from PDF title page (EBSCO, viewed March 19, 2019) |
| Subject |
Retina -- Diseases.
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Choroid -- Diseases.
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Central Serous Chorioretinopathy
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Retinal Diseases
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Choroid Diseases
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MEDICAL -- Surgery -- General.
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MEDICAL -- Diseases.
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Choroid -- Diseases
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Retina -- Diseases
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| Form |
Electronic book
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| Author |
Chhablani, Jay, editor.
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| ISBN |
9780128173015 |
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0128173017 |
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9780128168004 |
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0128168005 |
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