Preface -- Screening for cervical cancer precursors to prevent invasive disease -- Methods of obtaining and preparing cervical tissue for histological examination. Diagnostic or therapeutic procedures ; Preparation of the cervical specimen -- Immunohistochemistry and in situ hybridization. Immunohistochemistry ; In situ hybridization -- Normal histology, regeneration, and repair. Normal ectocervix ; Ascending repair ; Normal endocervix ; Descending repair ; Transformation zone -- Vestigial and heterotopic tissues. Mesonephric duct remnants and hyperplasia ; Mèullerian duct remnants and metaplasia ; Heterotopic ectodermal and mesodermal structures -- Hormonally induced changes. Effects of estrogen ; Effects of endogenous progesterone under hypersecretion ; Effects of exogenous gestagens ; Glandular papillary ectropium ; Polyps of the ecto- and endocervix -- Inflammatory lesions. Nonspecific ecto- and endocervicitis ; Specific inflammations ; Irradiation changes ; Postoperative spindle cell nodule -- Benign tumors. Epithelial tumors ; Mesenchymal tumors ; Mixed tumors -- Premalignant lesions. Introduction ; Etiology and pathogenesis ; Histopathology and immunohistochemistry -- Malignant tumors. Epithelial tumors ; Mesenchymal tumors ; Mixed epithelial and mesenchymal tumors ; Miscellaneous tumors ; Secondary tumors
Summary
"The second edition of this atlas provides a detailed histopathological diagnosis of cervical disease emphasizing carcinogenesis and correlating morphologic changes with clinical aspects. Instructions on how to obtain and handle tissue samples are followed by a description of the normal histology, the action of steroid hormones on the cervix, and the various forms of regeneration and inflammation. The section on etiology and pathogenesis of HPV-induced neoplasia has been enlarged to explain new insights into cellular and nuclear deregulation at the molecular level."--Jacket
Analysis
geneeskunde
medicine
volksgezondheid
public health
gynaecologie
gynaecology
pathologie
pathology
oncologie
oncology
Medicine (General)
Geneeskunde (algemeen)
Bibliography
Includes bibliographical references (pages 180-191) and index
