| Description |
1 online resource (xii, 571 pages) : illustrations |
| Contents |
1. Introduction to applications of microdialysis in pharmaceutical science / Tung-Hu Tsai -- 2. Microdialysis in drug discovery / Christian Höcht -- 3. Analytical considerations for microdialysis sampling / Pradyot Nandi, Courtney D Kuhnline, Susan M Lunte -- 4. Monitoring dopamine in the mesocorticolimbic and nigrostriatal systems by microdialysis : relevance for mood disorders and Parkinson's Disease / Giuseppe di Giovanni, Massimo Pierucci, Vincenzo Di Matteo -- 5. Monitoring neurotransmitter amino acids by microdialysis : pharmacodynamic applications / Sandrine Parrot [and others] -- 6. Microdialysis as a tool to unravel neurobiological mechanisms of seizures and antiepileptic drug action / Ilse Smolders, Ralph Clinckers, Yvette Michotte -- 7. Microdialysis in lung tissue : monitoring of exogenous and endogenous compounds / Thomas Feurstein, Markus Zeitlinger -- 8. Microdialysis in the hepatobiliary system: monitoring drug metabolism, hepatobiliary excretion, and enterohepatic circulation / Yu-Tse Wu, Tung-Hu Tsai -- 9. Microdialysis used to measure the metabolism of glucose, lactate, and glycerol / Greg Nowak -- 10. Clinical microdialysis in skin and soft tissues / Martina Sahre, Runa Naik, Hartmut Derendorf -- 11. Microdialysis on adipose tissue : monitoring tissue metabolism and blood flow in humans / Gijs H Goossens, Wim H.M. Saris, Ellen E Blaak -- 12. Microdialysis as a monitoring system for human diabetes / Anna Ciechanowska [and others] -- 13. Microdialysis use in tumors: drug disposition and tumor response / Qingyu Zhou, James M Gallo -- 14. Microdialysis versus imaging techniques for in vivo drug distribution measurements / Martin Brunner -- 15. In vitro applications of microdialysis / Wen-Chuan Lee, Tung-Hu Tsai -- 16. Microdialysis in drug interaction / Mitsuhiro Wada, Rie Ikeda, Kenichiro Nakashima -- 17. Microdialysis in environmental monitoring / Manuel Miró, Wolfgang Frenzel |
| Summary |
"This book emphasizes the applications of microdialysis in different organs and tissues for pharmacokinetic and pharmacodynamic studies, covering the range of current clinical uses for microdialysis. Along with details of the basics of this analytical technique, topics in the book include applications for drug discovery, analytical consideration of samples, neurological disease investigations, sampling at different organs, diabetes evaluations, tumor response estimations and comparison of microdialysis"-- Provided by publisher |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
|
Print version record |
| Subject |
Dialysis.
|
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Pharmaceutical chemistry.
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Drug development.
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Chemistry, Pharmaceutical -- methods
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Microdialysis -- methods
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Dialysis
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Chemistry, Pharmaceutical
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MEDICAL -- Drug Guides.
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MEDICAL -- Nursing -- Pharmacology.
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MEDICAL -- Pharmacology.
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MEDICAL -- Pharmacy.
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Dialysis
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Drug development
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Pharmaceutical chemistry
|
| Form |
Electronic book
|
| Author |
Tsai, Tung-Hu.
|
| LC no. |
2011010963 |
| ISBN |
9781118011294 |
|
1118011295 |
|
9781118011270 |
|
1118011279 |
|
9781118011287 |
|
1118011287 |
|
1283203774 |
|
9781283203777 |
|
9786613203779 |
|
6613203777 |
|
