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Title Biology and treatment of leukemia and bone marrow neoplasms / Vinod Pullarkat, Guido Marcucci, editors
Published Cham : Springer, [2021]


Description 1 online resource : illustrations (chiefly color)
Series Cancer treatment and research, 2509-8497 ; volume 181
Cancer treatment and research ; v. 181. 2509-8497
Contents Advances in diagnosis and risk stratification of leukemias and bone marrow neoplasms -- Genetics and diagnostic approach to lymphoblastic leukemia -- Acute promyelocytic leukemia: update on risk stratification and treatment -- Current and emerging therapies for AML -- Current management and new developments in treatment of ALL -- Contemporary therapy of CML -- MDS: Pathogenesis and therapy -- Chronic lymphocytic leukemia: Biology and therapy -- Biology and current treatment of Myeloproliferative neoplasms -- Systemic Mastocytosis: Pathology and treatment -- Adoptive T-cell therapy and other novel immunotherapies for leukemia
Summary This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students
Notes Online resource; title from PDF title page (SpringerLink, viewed October 18, 2021)
Subject Acute leukemia.
Acute leukemia -- Treatment
Chronic leukemia.
Chronic leukemia -- Treatment
Bone marrow -- Tumors.
Bone marrow -- Tumors -- Treatment
Bone Marrow Neoplasms
Acute leukemia
Acute leukemia -- Treatment
Bone marrow -- Tumors
Chronic leukemia
Medul·la òssia.
Quimioteràpia del càncer.
Ciències de la salut.
Genre/Form Electronic books
Llibres electrònics.
Form Electronic book
Author Pullarkat, Vinod, editor.
Marcucci, Guido, editor
ISBN 9783030783112