A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling
A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling
Coffey, Edward Lees : Report from the Select Committee on Ameer Ali Moorad's Claim (Coffey's petition) together with the proceedings of the committee, minutes of evidence, appendix and index
Coffin texts. : Historical and archaeological aspects of Egyptian funerary culture : religious ideas and ritual practice in Middle Kingdom elite cemeteries / by Harco Willems
Coffman, Don Ferdinand : The execution of William McCauley : the only legal hanging that ever occurred in Van Buren County : an interesting and authentic history of the crime, confession, trial and execution / compiled from the records by E.R. Harlan
