| Description |
1 online resource (xii, 240 pages) : illustrations |
| Contents |
Phenotype and functional genomics : introduction -- Evolution -- Genomic architecture and copy number changes -- Linkage, association, and linkage disequilibrium -- Regulation of transcription, splicing, and translation : impact of perturbation on phenotype -- Mitochondria : genome, functions, and phenotype -- Quality surveillance -- Neurodevelopment and functional genomics -- Neurobehavioral disorders -- Molecular analyses of malformation syndromes -- Multiple pathways including environmental factors that lead to a specific phenotype with later onset |
| Summary |
During the past two decades international collaborative studies have yielded extensive information on genome sequences, genome architecture and their variations. The challenge we now face is to understand how these variations impact structure and function of organelles, physiological systems and phenotype. The goal of this book is to present steps in the pathways of exploration to connect genotype to phenotype and to consider how alterations in genomes impact disease. In this book the author reviews published research in functional genomics carried out primarily since 2006 that sheds light on |
| Bibliography |
Includes bibliographical references (pages 200-227) and index |
| Notes |
English |
|
Print version record |
| Subject |
Phenotype.
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Phenotypic plasticity.
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Genomics.
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Human genetics -- Variation.
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Genetic Variation
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Phenotype
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Congenital Abnormalities -- genetics
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Genomics
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Nervous System Diseases -- genetics
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SCIENCE -- Life Sciences -- Genetics & Genomics.
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Human genetics -- Variation
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Genomics
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Phenotype
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Phenotypic plasticity
|
| Form |
Electronic book
|
| LC no. |
2010004048 |
| ISBN |
9780199702046 |
|
0199702047 |
|
1283121220 |
|
9781283121224 |
|
0199975213 |
|
9780199975211 |
|
9786613121226 |
|
6613121223 |
|
