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E-book

Title Management of hereditary colorectal cancer : a multidisciplinary approach / Jose G. Guillem, Garrett Friedman, editors
Published Cham : Springer, 2020

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Description 1 online resource (213 pages)
Contents Intro -- Contents -- Contributors -- Introduction -- 1: Early-Age-of-Onset Colorectal Carcinoma: An Emerging Public Health Issue -- Increasing Incidence of CRC in Young Adults Is a Global Health Issue -- Reasons for Increasing Incidence of CRC in Young Adults Are Not Known -- Currently Known Risk Factors for CRC May Not Be Relevant for Young Adults -- Current Data on Risk Factors for CRC in Young Adults Are Limited -- Population-Based CRC Screening Programs Do Not Cover Young Adults -- Current CRC Screening Guidelines Are Limited in Use for Young Adults
Most CRC in Young Adults Present in Late Stages -- Burden of Young Adult CRC Is Huge -- Risk-Based Screening Is a Way to Reduce the CRC Burden in Young Adults -- References -- 2: Management of Hamartomatous Polyps -- Introduction -- Peutz-Jeghers Syndrome -- Radiologic Imaging in PJS -- Endoscopy in PJS -- Surveillance -- Management of PJS -- Juvenile Polyposis Syndrome -- Surveillance and Management -- PTEN Hamartoma Tumor Syndrome -- Summary -- References -- 3: Familial Adenomatous Polyposis: Prophylactic Management of the Colon and Rectum -- Introduction -- Clinical Presentation
Diagnosis and Screening -- Genetics -- Chemoprevention -- Surgical Management -- IRA Versus IPAA -- Mucosectomy and Handsewn IPAA Versus Stapled IPAA -- Minimally Invasive (MIS) Versus Open Surgery -- Type of Ileal Pouch -- Postoperative Surveillance -- Quality of Life -- Conclusion -- References -- 4: FAP Surveillance Post IPAA or IRA -- Introduction -- Total Proctocolectomy and Ileal Pouch-Anal Anastomosis -- Endoscopic Screening Surveillance Recommendations Following Ileal Pouch-Anal Anastomosis -- Medical Management of Adenomatous Polyps Following Ileal Pouch-Anal Anastomosis
Surgical Management of Polyps Following Ileal Pouch-Anal Anastomosis -- Cancer Management Following Ileal Pouch-Anal Anastomosis -- Total Abdominal Colectomy with Ileorectal Anastomosis -- Surveillance and Management of the Rectum Following Ileorectal Anastomosis -- Desmoid Tumors and Completion Proctectomy Following Ileorectal Anastomosis -- Conclusions -- References -- 5: Familial Adenomatous Polyposis: Management of Upper Gastrointestinal Polyps -- Introduction -- Gastric Neoplasia -- Gastric Fundic Gland Polyps -- Gastric Adenomas -- Duodenal Neoplasia -- Duodenal Adenomas
Ampullary Adenomas -- Management of Gastric and Duodenal Neoplasms -- Screening and Surveillance -- Gastric Polyps -- Duodenal Adenomas -- Ampullary Adenomas -- Endoscopic Resection of Gastric and Duodenal Neoplasms -- Endoscopic Resection of Ampullary Adenomas -- Surgical Resection of Duodenal and Ampullary Neoplasms -- Chemoprevention -- Sulindac -- Celecoxib -- Agents Under Investigation -- Summary -- References -- 6: Desmoids in Familial Adenomatous Polyposis -- What Are Desmoids? -- Epidemiology -- Desmoids in FAP -- Desmoid Formation -- Growth and Progression
Summary This book provides a comprehensive review of the clinical management of hereditary colorectal cancer. The text focuses on six distinct patient groups: patients with elderly age-of-onset colorectal cancer and adenomas, patients with hamartomatous colorectal polyps, patients afflicted with familial adenomatous polyposis (FAP), patients with attenuated familial adenomatous polyposis (AFAP), patients with MYH associated polyposis (MAP), and patients afflicted with lynch syndrome (LS). Each chapter illustrates how clinicians utilize current technologies in genetic testing, pathological review, and endoscopic, surgical, and chemotherapeutic/immunotherapeutic approaches to manage these patient groups. Topics such as the timing of genetic testing, endoscopic screening and surveillance, prophylactic surgical options and chemo-preventive interventions are also discussed in concise yet precise detail. Written by experts in their fields, Management of Hereditary Colorectal Cancer: A Multidisciplinary Approach is a valuable and timely resource for gastroenterologists, surgeons, genetic counselors, medical oncologists, psychologists, and any health caregivers involved with the management of patients and families afflicted with a hereditary form of colorectal cancer.
Notes Risk Factors for Desmoid Formation
Print version record
Subject Colon (Anatomy) -- Cancer -- Treatment
Rectum -- Cancer -- Treatment
Colonic Neoplasms -- congenital
Colonic Neoplasms -- immunology
Colonic Neoplasms -- prevention & control
Gastroenterology
Surgery.
Oncology.
Gastroenterology.
Medical -- Surgery -- General.
Medical -- Oncology.
Medical -- Gastroenterology.
Colon (Anatomy) -- Cancer -- Treatment
Rectum -- Cancer -- Treatment
Genre/Form Electronic books
Form Electronic book
Author Guillem, Jose G
Friedman, Garrett
ISBN 9783030262341
3030262340