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Title Cocaine abuse : behavior, pharmacology, and clinical applications / [edited by] Stephen T. Higgins, Jonathan L. Katz
Published San Diego, Calif. : Academic Press, ©1998


Description 1 online resource (xxiv, 445 pages) : illustrations
Contents Basic pharmacological mechanisms of cocaine -- Neuroanatomical bases of the reinforcing stimulus effects of cocaine -- Behavioral pharmacology of cocaine and the determinants of abuse liability -- Behavioral-environmental determinants of the reinforcing functions of cocaine -- Tolerance and sensitization to cocaine: an integrated view -- Preclinical evaluation of pharmacotherapies for cocaine abuse -- Prenatal exposure to cocaine -- Cocaine self-administration research: implications for rational pharmacotherapy -- Evaluation of potential pharmacotherapies: response to cocaine challenge in the human laboratory -- Controlled laboratory studies on the effects of cocaine in combination with other commonly abused drugs in humans -- Cocaine effects on brain function -- Contribution of genetic factors in cocaine and other drug abuse -- Vulnerability to cocaine abuse -- Treating cocaine abuse: what does research tell us? -- Treatment of cocaine abuse in methadone maintenance patients -- Relapse to cocaine use -- Cocaine legalization: designing the experiments
Summary Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. Cocaine abuse results from a complex interplay of behavioral, pharmacological, and neurobiological determinants. While a complete understanding of cocaine abuse is currently beyond us, significant progress has been made in preclinical research on fundamental determinants of this disorder. These advances are critically reviewed in the first section of this volume. Important advances also have
Bibliography Includes bibliographical references and index
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Print version record
Subject Cocaine abuse -- Pathophysiology
Cocaine abuse -- Treatment
Cocaine -- Psychological aspects.
Cocaine abuse.
Behavior -- drug effects
Cocaine -- pharmacology
Cocaine-Related Disorders -- therapy
Cocaine-Related Disorders
HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain)
MEDICAL -- Neurology.
Cocaine abuse.
Cocaine abuse -- Treatment.
Cocaine -- Psychological aspects.
Social services & welfare, criminology.
Behavioural theory (Behaviourism)
Addiction & therapy.
Psychology: states of consciousness.
Clinical psychology.
Coping with drug & alcohol problems.
Form Electronic book
Author Higgins, Stephen T.
Katz, Jonathan L.
ISBN 9780080529264