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Book Cover
E-book
Author IMA Workshop on Mathematics of DNA Structure, Function, and Interactions (2007 : Minneapolis, Minn.)

Title Mathematics of DNA structure, function and interactions / Craig John Benham [and others], editors
Published Dordrecht ; New York : Springer, ©2009

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Description 1 online resource (xii, 351 pages) : illustrations (some color)
Series The IMA volumes in mathematics and its applications, 0940-6573 ; 150
IMA volumes in mathematics and its applications ; 150
Contents Cover -- Contents -- Foreword -- Preface -- Nick Cozzarelli: A personal remembrance -- Mathematical methods in DNA topology: Applications to chromosome organization and site-specific recombination -- Conformational statistics of DNA and diffusion equations on the Euclidean group -- Perspectives on DNA looping -- Differences between positively and negatively supercoiled DNA that topoisomerases may distinguish -- Calibration of tethered particle motion experiments -- Difference topology: Analysis of high-order DNA-protein assemblies -- Useful intrusions of DNA topology into experiments on protein-DNA geometry -- Topological analysis of DNA-protein complexes -- Closing the loop on protein-DNA interactions: Interplay between shape and flexibility in nucleoprotein assemblies having implications for biological regulation -- Four-way helical junctions in DNA molecules -- Micromechanics of single supercoiled DNA molecules -- Flexibility of nucleosomes on topologically constrained DNA -- The mathematics of DNA structure, mechanics, and dynamics -- Paradox regained: a topological coupling of nucleosomal DNA wrapping and chromatin fibre coiling -- Statistical-mechanical analysis of enzymatic topological transformations in DNA molecules -- List of workshop participants
Summary Propelled by the success of the sequencing of the human and many related genomes, molecular and cellular biology has delivered significant scientific breakthroughs. Mathematics (broadly defined) continues to play a major role in this effort, helping to discover the secrets of life by working collaboratively with bench biologists, chemists and physicists. Because of its outstanding record of interdisciplinary research and training, the IMA was an ideal venue for the 2007-2008 IMA thematic year on Mathematics of Molecular and Cellular Biology. The kickoff event for this thematic year was a tutorial on Mathematics of Nucleic Acids, followed by the workshop Mathematics of Molecular and Cellular Biology, held September 15--21 at the IMA. This volume is dedicated to the memory of Nicholas R. Cozzarelli, a dynamic leader who fostered research and training at the interface between mathematics and molecular biology. It contains a personal remembrance of Nick Cozzarelli, plus 15 papers contributed by workshop speakers. The papers give and overview of state-of-the-art mathematical approaches to the understanding of DNA structure and function, and the interaction of DNA with proteins that mediate vital life processes
Analysis wiskunde
mathematics
mathematische biologie
mathematical biology
systeembiologie
systems biology
toegepaste wiskunde
applied mathematics
Mathematics (General)
Wiskunde (algemeen)
Bibliography Includes bibliographical references
Notes Print version record
In Springer - LINK
Subject Biomathematics -- Congresses
DNA -- Congresses
DNA -- Structure -- Congresses
DNA-protein interactions -- Congresses
DNA.
DNA
NATURE -- Reference.
SCIENCE -- Life Sciences -- General.
SCIENCE -- Life Sciences -- Biology.
DNA -- Structure.
DNA-protein interactions.
Biomathematics.
DNA.
Biomathematics
DNA
DNA-protein interactions
DNA -- Structure
Genre/Form proceedings (reports)
Conference papers and proceedings
Conference papers and proceedings.
Actes de congrès.
Form Electronic book
Author Benham, Craig John.
LC no. 2009931719
ISBN 9781441906700
1441906703
1282333259
9781282333253