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Title TT viruses : the still elusive human pathogens / Ethel-Michele de Villiers, Harald zur Hausen, editors
Published Berlin : Springer, ©2009


Description 1 online resource (x, 230 pages) : illustrations (some color)
Series Current topics in microbiology and immunology ; v. 331
Current topics in microbiology and immunology ; 331.
Contents History of Discoveries and Pathogenicity of TT Viruses -- Classification of TTV and Related Viruses (Anelloviruses) -- TT Viruses in Animals -- Replication of and Protein Synthesis by TT Viruses -- Immunobiology of the Torque Teno Viruses and Other Anelloviruses -- Intragenomic Rearrangement in TT Viruses: A Possible Role in the Pathogenesis of Disease -- TT Viruses: Oncogenic or Tumor-Suppressive Properties? -- Relationship of Torque Teno Virus to Chicken Anemia Virus -- Apoptosis-Inducing Proteins in Chicken Anemia Virus and TT Virus -- Chicken Anemia Virus -- Geminiviruses
Summary Eleven years ago the circular DNA of a novel single-stranded virus has been cloned and partially characterized by Nishizawa and Okamoto and their colleagues. According to the initials of the patient from whom the isolate originated, the virus was named TT virus. This name has been subsequently changed by the International Committee on Taxonomy of Viruses (ICTV) into Torque teno virus, permitting the further use of the abbreviation TTV. Although initially suspected to play a role in non A -E hepatitis, subsequent studies failed to support this notion. Within a remarkably short period of time it became clear that TT viruses are widely spread globally, infect a large proportion of all human populations studied thus far and represent an extremely heterogeneous group of viruses, now labelled as Anelloviruses. TT virus-like infections have also been noted in various animal species. The classification of this virus group turns out to be difficult, their DNA contains between 2200 and 3800 nucleotides, related so-called TT-mini-viruses and a substantial proportion of intragenomic recombinants further complicate attempts to combine these viruses into a unifying phylogenetic concept
Bibliography Includes bibliographical references and index
Notes Print version record
Subject DNA viruses.
Torque teno virus.
DNA Virus Infections -- etiology
Torque teno virus -- pathogenicity
Chicken anemia virus -- pathogenicity
DNA Viruses
SCIENCE -- Life Sciences -- Biology.
SCIENCE -- Life Sciences -- Microbiology.
Torque teno virus -- pathogenicity.
Chicken anemia virus -- pathogenicity.
DNA viruses.
DNA Virus Infections -- etiology.
Sciences de la vie.
DNA viruses.
Torque teno virus.
Form Electronic book
Author De Villiers, Ethel-Michele.
Zur Hausen, Harald.
ISBN 9783540709725