| Description |
1 online resource (609 pages) : illustrations (some color) |
| Contents |
Front Cover; Contributors; ADVANCED TOPICS IN FORENSIC DNA TYPING: INTERPRETATION; Copyright; Dedication; Contents; Foreword; Introduction; NEW MATERIAL IN THIS VOLUME; OVERVIEW OF BOOK CHAPTERS; References; Acknowledgments; Reference; About the Author; Reference; SECTION I -DATA INTERPRETATION; Chapter 1 -- Data Interpretation Overview; PURPOSE OF THIS BOOK; THE INTERPRETATION PROCESS; CHARACTERISTICS OF IDEAL DATA; GUIDANCE FOR DNA INTERPRETATION; A MATCH OR NOT A MATCH: THAT IS THE QUESTION ... ; STR LOCI, KITS, AND POPULATION DATA; SUMMARY; Reading List and Internet Resources |
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Chapter 2 -- Data, Models, ThresholdsDATA COLLECTION IN ABI GENETIC ANALYZERS11CERTAIN COMMERCIAL EQUIPMENT, INSTRUMENTS, AND MATERIALS ARE IDENTIFIED IN ORDER ... ; MODELS; THRESHOLDS USED IN STR TYPING; SETTING AND USING ANALYTICAL THRESHOLDS; Reading List and Internet Resources; Chapter 3 -- STR Alleles and Amplification Artifacts; INTRODUCTION; OVERVIEW OF THE STR TYPING PROCESS; STR ALLELES AND THEIR MEASUREMENT; VARIANT AND "OFF-LADDER" ALLELES; ARTIFACTS OF STR ALLELE AMPLIFICATION; NON-TEMPLATE ADDITION; STUTTER PRODUCTS; NULL (SILENT) ALLELES; Reading List and Internet Resources |
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Chapter 4 -- STR Genotypes: Heterozygote Balance, Stochastic Thresholds, Allele, and Concordance StudiesIMPORTANCE OF GENOTYPES VS. ALLELES; PEAK HEIGHT RATIOS; STOCHASTIC THRESHOLDS AND ALLELE DROP-OUT; CONCORDANCE STUDIES AND NULL ALLELES; Reading List and Internet Resources; Chapter 5 -- STR Profiles: Multiplex PCR, Tri-Alleles, Amelogenin, and Partial Profiles; INTRODUCTION; MULTIPLEX PCR CHALLENGES; STR PROFILE EVALUATION; TRI-ALLELIC PATTERNS; GENDER IDENTIFICATION WITH AMELOGENIN; PARTIAL DNA PROFILES; Reading List and Internet Resources; Chapter 6 -- DNA Mixtures; GENERAL INFORMATION |
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TOOLS FOR MIXTURE INTERPRETATIONELEMENTS OF MIXTURE INTERPRETATION; RESOURCES AND GUIDANCE ON MIXTURE INTERPRETATION; COMPLICATING FACTORS IN MIXTURE DECONVOLUTION; Reading List and Internet Resources; Tools for Mixture Interpretation; Elements of Mixture Interpretation; Resources to Aid Mixture Interpretation; Chapter 7 -- Low-Level DNA and Complex Mixtures; INTERPRETATION CHALLENGES WITH LOW TEMPLATE DNA; LOW-QUANTITY AND LOW-QUALITY DNA; PROBABILISTIC GENOTYPING; HIGH-DENSITY SNP ARRAYS?; MORE POOR-QUALITY SAMPLES BEING SUBMITTED; A COMPLEXITY THRESHOLD?; Reading List and Internet Resources |
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Chapter 8 -- Troubleshooting Data CollectionINTRODUCTION; PRINCIPLES AND PROCESSES INVOLVED WITH CAPILLARY ELECTROPHORESIS; INSTRUMENT MAINTENANCE & COMMON PROBLEMS; RECOMMENDED STEPS FOR TROUBLESHOOTING; SUMMARY; Reading List and Internet Resources; SECTION II -- STATISTICALINTERPRETATION; Chapter 9 -- Statistical Interpretation Overview; ROLE OF STATISTICS IN FORENSIC DNA; PROBABILITY; STATISTICS; Reading List and Internet Resources; Chapter 10 -- STR Population Data Analysis; INTRODUCTORY GENETIC PRINCIPLES; POPULATION DATA; GENETIC MODELS AND FORMULAS; PRACTICAL CONSIDERATIONS; SUMMARY |
| Summary |
The first edition of Forensic DNA Typing, published in 2001, by John Butler quickly established itself as the gold-standard reference for the field. Over the next ten years, the vast amount of new information uncovered has resulted in this new volume, Advanced Topics in Forensic DNA Typing: Interpretation. This book builds upon the previous two editions of Forensic DNA Typing books, but with a focus on mixture interpretation and statistical analysis and is a companion to the bestselling Advanced Topics in Forensic DNA Typing: Methodology, published in September 2011. Provides forensic DNA ana |
| Bibliography |
Includes bibliographical references and index |
| Notes |
English |
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Print version record |
| Subject |
DNA fingerprinting -- Moral and ethical aspects
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DNA fingerprinting -- Congresses
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DNA Fingerprinting -- methods
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MEDICAL -- Forensic Medicine.
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MEDICAL -- Preventive Medicine.
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MEDICAL -- Public Health.
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DNA fingerprinting
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| Genre/Form |
Conference papers and proceedings
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| Form |
Electronic book
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| ISBN |
9780124058545 |
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012405854X |
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0124052134 |
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9780124052130 |
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