Description |
1 online resource (284 pages) : illustrations |
Series |
CRC Press methods in toxicology |
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CRC Press methods in the life sciences. Methods in toxicology.
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Contents |
Molecular techniques for developmental toxicology : an introduction / George P. Daston -- Visualization of gene expression patterns by in situ hybridization / Urs Albrecht, Gregor Eichele, Jill A. Helms, and Hui-Chen Lu -- Utilizing transgenic mice to study gene regulation and function / Michael R. Blackburn and Rodney E. Kellems -- Use of antisense oligonucleotide technology and mouse whole-embryo culture to study gene function during organogenesis / Linda F. Potts and T.W. Sadler -- Nucleic acid amplification technologies / Richard h. Finnell, Scott J. Vacha, and Scott A. Mackler -- Fundamentals of protein identification : biochemical and immunological analysis of developmentally altered protein expression / Gerald B. Grunwald -- Immunohistochemistry / Philip E. Mirkes and Sally A. Little -- Cellular techniques for teratological cell death / Thomas B. Knudsen -- Applications of flow cytometry in developmental and reproductive toxicolgy / Kenneth H. Elstein and Robert M. Zucker -- Modern techniques for cell labeling in avian and murine embryos / Diana K. Darnell and Gary C. Schoenwolf |
Summary |
This new manual provides a convenient source of experimental procedures, including the most modern and frequently used molecular and cellular techniques. Experimental protocols have been carefully selected by developmental toxicologists for developmental toxicologists. The most important new trends, such as evaluation of the safety of therapeutic antisense oligonucleotides, studies of the role of cell death in abnormal development, and the identification of sparingly expressed developmental control genes are featured. This is the perfect manual for scientists trained in classical developmental toxicology who want to add molecular and cellular methods to their research |
Bibliography |
Includes bibliographical references and index |
Notes |
Print version record |
Subject |
Developmental toxicology -- Methodology
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Molecular toxicology -- Methodology
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Cytology -- Methodology
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Toxicology.
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Cytology.
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Fetus -- drug effects
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Pregnancy -- drug effects
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Toxicology
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Cell Biology
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Molecular Biology
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Cytology
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toxicology.
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MEDICAL -- Gynecology & Obstetrics.
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MEDICAL -- Toxicology.
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SCIENCE -- Life Sciences -- Biology -- Molecular Biology.
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SCIENCE -- Life Sciences -- Biology -- Developmental Biology.
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Toxicology
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Cytology
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Cytology -- Methodology
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Developmental toxicology -- Methodology
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Molecular toxicology -- Methodology
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Teratogenitätstest
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Aufsatzsammlung
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Genre/Form |
Laboratory manuals
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Laboratory manuals.
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Manuels de laboratoire.
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Form |
Electronic book
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Author |
Daston, George P.
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ISBN |
9780429187193 |
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042918719X |
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9781439810668 |
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1439810664 |
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9780429526176 |
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0429526172 |
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9780429540875 |
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0429540876 |
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