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Book Cover
E-book
Author Cumming, Paul.

Title Imaging dopamine / Paul Cumming
Published Cambridge, UK ; New York : Cambridge University Press, 2009

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Description 1 online resource (xv, 340 pages, 12 unnumbered pages of plates) : illustrations (some color)
Contents The life history of dopamine -- Enzymology of tyrosine hydroxylase -- The assay of tyrosine hydroxylase -- Enzymology of aromatic amino acid decarboxylase -- PET studies of DOPA utilization -- Conjugation and sulfonation of dopamine and its metabolites -- Dopamine synthesis and metabolism rates -- MAO activity in the brain -- Vesicular storage of dopamine -- Dopamine release : from vesicles to behavior -- The plasma membrane dopamine transporter -- Dopamine receptors -- Imaging dopamine D1 receptors -- Imaging dopamine D2 receptors -- Factors influencing D2 binding in living brain -- The absolute abundance of dopamine receptors in brain
Summary Since its discovery 50 years ago, brain dopamine has been implicated in the control of movement and cognition, and is concerned with diverse brain diseases such as Parkinson's disease, schizophrenia and drug addiction. This book is an illustrated biography of the dopamine molecule, from its synthesis in the brain to its signalling mechanisms and ultimately to its metabolic breakdown. Using colour illustrations of positron emission tomography (PET) scans, each chapter presents a specific stage in the biochemical pathway for dopamine. Writing for researchers and graduate students, Paul Cumming presents a compilation of all that has been learned about dopamine through molecular imaging, a technology which allows the measurement of formerly invisible processes in the living brain. He reviews current technical controversies in the interpretation of dopamine imaging, and presents key results illuminating brain dopamine in illness and health
Bibliography Includes bibliographical references (pages 234-330) and index
Notes English
Print version record
Subject Dopamine.
Tomography, Emission.
Single-photon emission computed tomography.
Molecular radiobiology.
Dopamine
Tomography, Emission-Computed, Single-Photon
Tomography, Emission-Computed
MEDICAL -- Neuroscience.
PSYCHOLOGY -- Neuropsychology.
Dopamine
Molecular radiobiology
Single-photon emission computed tomography
Tomography, Emission
Dopamin.
Genre/Form Electronic books
Form Electronic book
ISBN 9780511534294
0511534299
9780511575853
0511575858
1107194792
9781107194793
1283331055
9781283331050
0511533985
9780511533983
9786613331052
6613331058
0511532482
9780511532481
0511531575
9780511531576