| Description |
1 online resource (xi, 369 pages) : illustrations |
| Series |
Journal of neural transmission ; suppl. 73 |
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Journal of neural transmission. Supplementum ; 73.
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| Contents |
Birth of dopaminergic neurons -- SNc dopaminergic neurons -- Death of SNc dopaminergic neurons -- Saving the SNc dopaminergic neurons |
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Part I: Birth of Dopaminergic Neurons. Ontogeny of Substantia Nigra Dopamine Neurons / R. Orme, R.A. Fricker-Gates, and M.A. Gates -- Part II: SNc Dopaminergic Neurons. Phenotype, Compartmental Organization and Differential Vulnerability of Nigral Dopaminergic Neurons / T. González-Hernández, D. Afonso-Oramas, and I. Cruz-Muros ; Specific Vulnerability of Substantia Nigra Compacta Neurons / M.P. Smidt ; The Nigrostriatal Pathway: Axonal Collateralization and Compartmental Specificity / L. Prensa, J.M. Giménez-Amaya, A. Parent, J. Bernácer, and C. Cebrián ; The Localization of Inhibitory Neurotransmitter Receptors on Dopaminergic Neurons of the Human Substantia Nigra / H.J. Waldvogel, K. Baer, and R.L.M. Faull ; Basal Ganglia Control of Substantia Nigra Dopaminergic Neurons / C.R. Lee and J.M. Tepper ; Substantia Nigra Control of Basal Ganglia Nuclei / E. Guatteo, M.L. Cucchiaroni, and N.B. Mercuri ; Electrophysiological Characteristics of Dopamine Neurons: A 35-Year Update / W.-X. Shi ; Chaotic Versus Stochastic Dynamics: A Critical Look at the Evidence for Nonlinear Sequence Dependent Structure in Dopamine Neurons / C.C. Canavier, and P.D. Shepard ; Age-Dependent Changes in Dopaminergic Neuron Firing Patterns in Substantia Nigra Pars Compacta / I. Yoshiyuki, T. Kozaki, Y. Isomura, S. Ito, and K.-I Isobe ; The Neurobiology of the Substantia Nigra Pars Compacta: from Motor to Sleep Regulation / M.M.S. Lima, A.B. Reksidler, and M.A.B.F. Vital ; NonMotor Function of the Midbrain Dopaminergic Neurons / C. Da Cunha, E.C. Wietzikoski, M. Bortolanza, P.A. Dombrowski, L.M. dos Santos, S.L. Boschen, E. Miyoshi, M.A.B.F. Vital, R. Boerngen-Lacerda, and R. Andreatini ; The Substantia Nigra, the Basal Ganglia, Dopamine and Temporal Processing / C.R.G. Jones, and M. Jahanshahi ; Electrophysiological and Neurochemical Characterization of 7-Nitroindazole and Molsidomine Acute and Sub-Chronic Administration Effects in the Dopaminergic Nigrostrial System in Rats / V. Di Matteo, M. Pierucci, A. Benigno, G. Orbán, G. Crescimanno, E. Esposito, and G. Di Giovanni -- Part III: Death of SNc Dopaminergic Neurons. Involvement of Astroglial Fibroblast Growth Factor-2 and Microglia in the Nigral 6-Ohda Parkinsonism and a Possible Role of Glucocorticoid Hormone on the Glial Mediated Local Trophism and Wound Repair / C. Silva, K. Fuxe, and G. Chadi ; Age and Parkinson's Disease-Related Neuronal Death in the Substantia Nigra Pars Compacta / N. Eriksen, A.K. Stark, and B. Pakkenberg ; Neurodegeneration in Parkinson's Disease: Genetics Enlightens Physiopathology / O. Corti, M. Fournier, and A. Brice ; In Vivo Microdialysis in Parkinson's Research / G. Di Giovanni, E. Esposito, and V. Di Matteo ; Inflammatory Response in Parkinsonism / C. Barcia, F. Ros, M.A. Carrillo, D. Aguado-Llera, C.M. Ros, A. Gómez, C. Nombela, V. de Pablos, E. Fernández-Villalba, and M.-T. Herrero ; Increase of Secondary Processes of Microglial and Astroglial Cells After MPTP-Induced Degeneration in Substantia Nigra Pars Compacta of Non Human Primates / C. Barcia, C.M. Ros, M.A. Carrillo, F. Ros, A. Gomez, V. de Pablos, V. Bautista-Hernández, A. Sánchez-Bahillo, E. Fernández Villalba, and M.-T. Herrero ; Distinct Effects of Intranigral L-DOPA Infusion in the MPTP Rat Model of Parkinson's Disease / A.B. Reksidler, M.M.S. Lima, P.A. Dombrowski, G.F. Barnabé, M.L. Andersen, S. Tufik, and M.A.B.F. Vital ; Cannabinoid CB₁Receptors are Early Down Regulated Followed by a Further Up Regulation in the Basal Ganglia of Mice with Deletion of Specific Park Genes / M. Garcıá-Arencibia, C. Garcıá, A. Kurz, J.A. Rodríguez-Navarro, S. Gispert-Sánchez, M.A. Mena, G. Auburger, J.G. de Yébenes, and J. Fernández-Ruiz -- Part IV: Saving the SNc Dopaminergic Neurons. Neurogenesis in Substantia Nigra of Parkinsonian Brains? / O. Arias-Carrión, E. Yamada, N. Freundlieb, M. Djufri, L. Maurer, G. Hermanns, B. Ipach, W.-H. Chiu, C. Steiner, W.H. Oertel, and G.U. Hóglinger ; Stem Cells and Cell Replacement Therapy for Parkinson's Disease / K.-C. Sonntag, F. Simunovic, and R. Sanchez-Pernaute ; Gene Therapy for Parkinson's Disease / T. Yasuhara, and I. Date ; Immunization as Treatment for Parkinson's Disease / D.B. Agbo, F. Neff, F. Seitz, C. Binder, W.H. Oertel, M. Bacher, and R. Dodel ; A Diet for Dopaminergic Neurons? / G. Di Giovanni ; Intake of Tomato-Enriched Diet Protects from 6-Hydroxydopamine-Induced Degeneration of Rat Nigral Dopaminergic Neurons / V. Di Matteo, M. Pierucci, G. Di Giovanni, L.K. Dragani, S. Murzilli, A. Poggi, and E. Esposito |
| Summary |
Explores the life cycle of dopaminergic neurons from their birth to death, the cause of Parkinson's disease, the second most common and disabling condition in the elderly population. This work reviews the mechanisms by which alterations cause neuronal death, therapeutic approaches and the evidence of a possible de novo neurogenesis in the SNc |
| Analysis |
geneeskunde |
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medicine |
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volksgezondheid |
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public health |
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neurologie |
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neurology |
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Medicine (General) |
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Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Print version record |
| Subject |
Dopaminergic neurons.
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Substantia nigra.
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Cell physiology.
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Neurons.
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Neurotransmitters.
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Cell Physiological Phenomena
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Neurons
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Neurotransmitter Agents
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Dopamine Agents
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Substantia Nigra
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Dopaminergic Neurons
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MEDICAL -- Neuroscience.
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PSYCHOLOGY -- Neuropsychology.
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Neurotransmitters
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Neurons
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Cell physiology
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Dopaminergic neurons
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Substantia nigra
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Substantia nigra.
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| Form |
Electronic book
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| Author |
Di Giovanni, Giuseppe.
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Di Matteo, Vincenzo.
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Esposito, Ennio.
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| ISBN |
9783211926604 |
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3211926607 |
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3211926593 |
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9783211926598 |
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