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Book Cover
Author Mohr, Stephanie Elizabeth, 1971- author.

Title First in fly : Drosophila research and biological discovery / Stephanie Elizabeth Mohr
Published Cambridge, Massachusetts : Harvard University Press, 2018


Description 1 online resource (xii, 257 pages) : illustrations
Contents Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity
Summary A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. This book notes insights uncovered by investigators using this model organism. The author draws on these "first in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.-- Provided by publisher
Bibliography Includes bibliographical references and index
Notes In English
Print version record
Subject Drosophila melanogaster -- Genetics
Drosophila melanogaster -- Physiology
Animal models in research.
Drosophila melanogaster -- genetics
Drosophila melanogaster -- physiology
Drosophila Proteins
Models, Animal
SCIENCE -- Life Sciences -- Zoology -- General.
SCIENCE / Life Sciences / Genetics & Genomics
Animal models in research
Drosophila melanogaster -- Genetics
Drosophila melanogaster -- Physiology
Form Electronic book
ISBN 9780674984721