| Description |
1 online resource (ix, 438 pages) : illustrations (some color) |
| Contents |
Cover; Contents; Foreword; Epidemiology and Causes of Drug Hypersensitivity; Epidemiology and Causes of Severe Cutaneous Adverse Reactions to Drugs; Chemical-Induced Contact Hypersensitivity in the Mouse Model; Lessons from Nickel Hypersensitivity: Structural Findings; Drugs as Haptens, Antigens, and Immunogens; The p-i Concept: Evidence and Implications; Tolerance Mechanisms to Small Molecular Compounds; HIV and Drug Hypersensitivity; Abacavir Hypersensitivity; Genetics of Severe Drug Hypersensitivity Reactions in Han Chinese; Nevirapine Hypersensitivity |
| Summary |
Drug hypersensitivities are immune-mediated reactions characterized by exanthems, fever and internal organ involvement. They represent a challenging field of research: many different drugs can induce a variety of clinical symptoms through multiple mechanisms of drug-host interaction, many of which are poorly understood. This is the first book to approach the phenomenon of drug hypersensitivity in a comprehensive manner. Besides epidemiological aspects, it addresses the immunological mechanisms underlying these complicated reactions which go far beyond the IgE-mediated drug allergies also consi |
| Bibliography |
Includes bibliographical references and indexes |
| Notes |
Print version record |
| Subject |
Drug allergy.
|
|
Drug Hypersensitivity
|
|
MEDICAL -- Immunology.
|
|
HEALTH & FITNESS -- Allergies.
|
|
HEALTH & FITNESS -- Diseases -- Immune System.
|
|
Drug allergy
|
|
Geneesmiddelen.
|
|
Overgevoeligheid.
|
|
Arzneimittelallergie -- Aufsatzsammlung.
|
| Form |
Electronic book
|
| Author |
Pichler, Werner J., 1949-
|
| ISBN |
9781435634046 |
|
1435634047 |
|
9783318014549 |
|
3318014540 |
|
