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Book Cover
E-book
Author Shunmugaperumal, Tamilvanan.

Title Biofilm eradication and prevention : a pharmaceutical approach to medical device infections / Tamilvanan Shunmugaperumal
Published Hoboken, N.J. : Wiley, ©2010

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Description 1 online resource
Contents Frontmatter -- Color Plates -- Development and Characterization of Biofilms. Introduction and Overview of Biofilm -- Rationale for Biofilm Eradication from Modern Medical Devices -- Pathogenesis of Device-Related Nosocomial Infections -- Biofilm Resistance₆Tolerance to Conventional Antimicrobial Agents -- Analytical Techniques Useful to Study Biofilms -- Biofilm -- Related Infections in Various Human Organs (Nondevice -- Related Chronic Infections). Biofilm-Related Infections in Ophthalmology -- Biofilm-Related Infections in the Oral Cavity -- Implications of Biofilm Formation in Chronic Wounds and in Cystic Fibrosis -- Drug Delivery Carriers to Eradicate Biofilm formation on Medical Devices. Strategies for Prevention of Device-Related Nosocomial Infections -- Liposomes as Drug Delivery Carriers to Biofilms -- Polymer-Based Antimicrobial Delivery Carriers -- Index
(Publisher-supplied data) Chapter 1. Introduction and Overview of Biofilm Chapter 2. Rationale for biofilm eradication from modern medical devices Chapter 3. Pathogenesis of device-related nosocomial infections Chapter 4. Biofilm resistance/tolerance to conventional antimicrobial agents Chapter 5. Analytical techniques useful to study biofilm Chapter 6. Biofilm-related infections in ophthalmology Chapter 7. Biofilm-related infections in oral cavity Chapter 8. Implications of biofilm formation in chronic wound and in cystic fibrosis Chapter 9. Strategies for prevention of device-related nosocomial infections Chapter 10. Liposomes as drug delivery carriers to biofilms Chapter 11. Polymer-based antimicrobial delivery carriers
Summary "Biofilm Eradication and Preventions presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers need to take to limit this problem. Split into three parts, the first deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Questions as to why biofilms form over medical device surfaces and what triggers biofilm formation are addressed. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these area. The third part explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. In addition, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation"--Provided by publisher
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Medical instruments and apparatus -- Microbiology.
Biofilms.
Medical instruments and apparatus -- Sterilization.
Biofilms
Anti-Infective Agents -- therapeutic use
Drug Carriers -- therapeutic use
Prostheses and Implants -- microbiology
Prosthesis-Related Infections -- prevention & control
MEDICAL -- Instruments & Supplies.
Biofilms
Medical instruments and apparatus -- Microbiology
Medical instruments and apparatus -- Sterilization
Form Electronic book
ISBN 9780470640463
0470640464
9780470640456
0470640456
0470479965
9780470479964
1282653687
9781282653689