| Description |
1 online resource (450 pages) |
| Contents |
Preface; 1 Introduction to Pharmacokinetics and Pharmacodynamics; 2 Passage of Drugs Through Membranes; 3 Drug Administration, Absorption, and Bioavailability; 4 Drug Distribution; 5 Drug Elimination and Clearance; 6 Compartmental Models in Pharmacokinetics; 7 Pharmacokinetics of an Intravenous Bolus Injection in a One-Compartment Model; 8 Pharmacokinetics of an Intravenous Bolus Injection in a Two-Compartment Model; 9 Pharmacokinetics of Extravascular Drug Administration; 10 Introduction to Noncompartmental Analysis |
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11 Pharmacokinetics of Intravenous Infusion in a One-Compartment Model12 Multiple Intravenous Bolus Injections in the One-Compartment Model; 13 Multiple Intermittent Infusions; 14 Multiple Oral Doses; 15 Nonlinear Pharmacokinetics; 16 Introduction to Pharmacodynamic Models and Integrated Pharmacokinetic-Pharmacodynamic Models; 17 Mechanism-Based Integrated Pharmacokinetic-Pharmacodynamic Models; Appendix A Review of Exponents and Logarithms; Appendix B Rates of Processes; Appendix C Creation of Excel Worksheets for Pharmacokinetic Analysis |
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Appendix D Derivation of Equations for Multiple Intravenous Bolus InjectionsAppendix E Summary of the Properties of the Fictitious Drugs Used in the Text; Appendix F Computer Simulation Models; Glossary of Abbreviations and Symbols; Index |
| Summary |
This is a straightforward, uncomplicated, basic, introductory book that presents only the material essential to provide a good foundation in pharmacokinetics and pharmacodynamics â€" € designed by the author to teach quantitative pharmacokinetics and pharmacodynamics (PK and PD) in a novel way. It consists of the book and integrated interactive computer modules. Modules and exercises based on them are are available online via a companion website, and they are integrated into relevant parts of the book to reinforce the concepts presented there. The modules allow students to carry out and e |
| Bibliography |
Includes bibliographical references |
| Notes |
Print version record |
| Subject |
Pharmacokinetics -- Textbooks
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Pharmacokinetics -- Computer simulation
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Drugs -- Physiological effect -- Textbooks
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Drugs -- Physiological effect -- Computer simulation
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Pharmacokinetics.
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Pharmacokinetics
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Computer Simulation
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Pharmacological Phenomena
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simulation.
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MEDICAL -- Pharmacology.
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Drugs -- Physiological effect
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Pharmacokinetics
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Pharmacokinetics -- Computer simulation
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| Genre/Form |
Textbooks
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| Form |
Electronic book
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| ISBN |
9781118001059 |
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1118001052 |
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9780470569061 |
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0470569069 |
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1283052393 |
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9781283052399 |
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9786613052391 |
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6613052396 |
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