| Description |
1 online resource (xii, 220 pages) : illustrations |
| Series |
Book cum disc |
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Book cum disk
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| Contents |
1. Anatomy and physiology of the cochlea / Karen S. Pawlowski -- 2. Physiology of the vestibular system / John A. Rutka -- 3. Salicylates, nonsteroidal anti-inflammatory drugs, quinine, and heavy metals / Narayanan Prepageran and John A. Rutka -- 4. Ototoxicity of loop diuretics / Narayanan Prepageran, Andrew R. Scott and John A. Rutka -- 5. Cinical uses of Cisplatin / Jeremy Sturgeon -- 6. Ototoxicity of platinum compounds / Michael Anne Gratton and Brendan J. Smyth -- 7. Iron chelating and other chemotherapeutic agents : the vinca alkaloids / Andrew R. Scott, Narayanan Prepageran and John A. Rutka -- 8. Clinical aminoglycoside ototoxicity / Coleman Rotstein and Lionel A. Mandell -- 9. Mechanisms for aminoglycoside ototoxicity : basic science research / Jochen Schacht -- 10. Macrolides / Andrew R. Scott and John A. Rutka -- 11. Middle ear effects of ototopical agents / Charles G. Wright and Peter S. Roland -- 12. Topical aminoglycoside cochlear toxicity / Peter S. Roland and Charles G. Wright -- 13. Topical aminoglycoside vestibular toxicity / Narayanan Prepageran, Vitaly E. Kisilevsky and John A. Rutka -- 14. Chloramphenicol, colymycin, and polymyxin / Leonard P. Rybak and Srinivasan Krishna -- 15. Topical antifungals / Lawrence W.C. Tom, Lisa M. Elden and Roger R. Marsh -- 16. Surgical disinfectants and antiseptics / Andrew R. Scott, Narayanan Prepageran and John A. Rutka -- 17. Genetic factors in aminoglycoside ototoxicity / Nathan Fischel-Ghodsian -- 18. Audiologic monitoring for ototoxicity / Kathleen C.M. Campbell -- 19. Monitoring vestibular ototoxicity / Vitaly E. Kisilevsky, R. David Tomlinson, Paul Ranalli and Narayanan Prepageran -- 20. Ototoxic damage to hearing : otoprotective therapies / Thomas R. Van De Water and Leonard P. Rybak -- 21. Systemic treatment of bilateral Meniere's disease / Sumit K. Agrawal and Lorne S. Parnes -- 22. Intratympanic gentamicin in the treatment of Meniere's disease / Brian W. Blakley -- 23. Medicolegal aspects of ototoxicity / Peter E. Rhatican, Sloan H. Mandel and John A. Rutka -- App. 1. Information provided to lawyers -- App. 2. Summary of the 2004 AAO-HNS consensus panel recommendations -- App. 3. Major groups of agents recognized to be ototoxic in humans |
| Summary |
"This original text on ototoxicity belongs in the hands of every doctor who prescribes certain systemic or topical drugs - such as the aminoglycosides - and everyone who sees patients with ear disorders." "Written by experts in the field, the text reviews all classes of medication known to cause functional impairment and cellular damage to the tissues of the middle ear - especially the end organs of the cochlear and vestibular divisions of the eight cranial nerves. The text opens with basic anatomy and physiology and continues with clinical manifestations of ototoxicity, pathophysiology, prevention, and treatment, and medical-legal issues for each class of compounds. Case presentations, followed by discussion, illustrate key medicolegal concepts."--Jacket |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
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Print version record |
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committed to retain 20170930 20421231 HathiTrust https://www.hathitrust.org/shared_print_program{HathiTrust Shared Print commitment 2017} AEU |
| Subject |
Middle ear -- Effect of drugs on
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Cochlea -- Effect of drugs on
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Vestibular apparatus -- Effect of drugs on
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Aminoglycosides -- Toxicology
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Ear -- Diseases -- Chemotherapy
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Cochlea -- drug effects
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Ear, Middle -- drug effects
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Aminoglycosides -- toxicity
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Ear Diseases -- drug therapy
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Hearing Disorders -- chemically induced
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Vestibular Nerve -- drug effects
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Aminoglycosides -- Toxicology.
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Vestibular apparatus -- Effect of drugs on.
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| Form |
Electronic book
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| Author |
Roland, Peter S
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Rutka, John A
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