| Description |
1 online resource (xv, 119 pages) : illustrations (some color) |
| Contents |
Intro; Frugal Bioengineering: Preface and Introduction; Acknowledgments; References; Contents; Advances in Point-of-Care Diagnostics for Infectious Disease; 1 Introduction; 2 Cell Detection Tests; 3 Antigen/Antibody Detection Tests; 4 Nucleic Acid Tests; 5 Summary; 6 Technology and Infrastructure Gaps; References; Lab-on-DVD: Optical Disk Drive-Based Platforms for Point-of-Care Diagnostics; 1 Introduction; 2 Working Principle of Optical Drive Systems; 2.1 Detection Principles; 3 Lab-on-DVD Platform; 3.1 Absorbance Mode; 3.2 Imaging Mode |
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3.3 Additional Hardware Modifications Converting a Drive into a Bioanalytical Prototype; 4 Bioapplications; 4.1 Cellular Diagnostics; 4.2 Molecular Diagnostics; 5 Conclusions; References; High-Performance Paper Microfluidic Malaria Test for Low-Resource Settings; 1 Introduction and Motivation; 2 Current Methods and Limitations; 2.1 Laboratory-Based Tests: Microscopy and ELISA; 2.2 Lateral Flow Tests; 3 Paper Microfluidics as a Solution; 4 Experimental Methods; 4.1 Malaria Immunoassay System; 4.2 Device Materials and Fabrication; 4.3 Reagents on Membranes |
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4.4 Data Acquisition and Analysis; 5 Automated Multistep Sample Processing in Paper; 5.1 Device Geometry; 5.2 Dissolvable Fluidic Barriers; 5.3 Absorbent Fluidic Shunts; 6 Summary and Future; References; Microfluidics for Fast and Frugal Diagnosis of Malaria, Sepsis, and HIV/AIDS; 1 Introduction; 2 Sepsis; 2.1 Microfluidics for Diagnosis of Sepsis; 2.2 Microfluidic for Treatment of Sepsis; 3 Malaria; 4 HIV Infection and AIDS; 5 Commercial Developments; 6 Conclusions and Outlook; References; Perspective from Industry: AROMICS; 1 Overview; 1.1 Therapeutic Pipeline |
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1.2 Diagnostic Pipeline; 2 Current Need and Approach; 2.1 Our Approach in Infectious Diseases Area; 3 Technologies; 3.1 Fundamental Aspects of a Biosensor; 3.2 Integration of the Different Parts of Biosensor and Miniaturization; 4 Technologies as They Relate to Frugal Innovation; 5 Technical Aspects; 6 Lessons Learned with a Biotech Start-Up; 7 Concluding Remarks; References; Funding Frugal Innovation in Global Health: Philanthropy, Aid, and Industry; 1 Introduction; 2 Frugal Innovation and Engineering in Global Health; 3 Innovating on Frugal Innovation; 3.1 Evaluate Impact |
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3.2 Better Bridge Between Philanthropy/Aid and Industry; 3.2.1 Bridge Directly; 3.2.2 Strengthen the Support; 4 Conclusion; Notes and References; Concluding Remarks; References; Index |
| Summary |
This book introduces readers to the concept of 'frugal innovation' and describes novel low-cost technologies that aid in diagnosing infectious diseases. Rapidly deployable, portable, and affordable diagnostic tools have the potential to tremendously benefit populations in resource-limited settings and improve global health outcomes. Specifically, the book includes the following features: Cutting-Edge Research: Thorough coverage of scientific advances related to frugal bioengineering that have been developed within the last few years. A few examples of technologies covered in detail include low-cost paper-based and CD-based microfluidic diagnostic systems. Industry and Non-Profit Voices: Chapters written by scientists currently working in industry and philanthropic sectors |
| Notes |
Online resource; title from PDF title page (SpringerLink, viewed February 6, 2018) |
| Subject |
Biomedical engineering.
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Communicable diseases -- Epidemiology -- Technological innovations
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Diffusion of innovations.
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Communicable Diseases -- diagnosis
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Equipment Design -- economics
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Bioengineering -- economics
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Delivery of Health Care -- economics
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Diffusion of Innovation
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Biomedical Engineering
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Biomedical Technology
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biomedical engineering.
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Biomedical engineering.
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Public health & preventive medicine.
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Infectious & contagious diseases.
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HEALTH & FITNESS -- Holism.
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HEALTH & FITNESS -- Reference.
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MEDICAL -- Alternative Medicine.
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MEDICAL -- Atlases.
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MEDICAL -- Essays.
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MEDICAL -- Family & General Practice.
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MEDICAL -- Holistic Medicine.
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MEDICAL -- Osteopathy.
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Diffusion of innovations
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Biomedical engineering
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| Form |
Electronic book
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| Author |
Chavali, Arvind K., editor
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Ramji, Ramesh, editor
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| ISBN |
9783319666471 |
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3319666479 |
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