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Title Vascular-targeted therapies in oncology / editor, Dietmar W. Siemann
Published Chichester, West Sussex, England ; Hoboken, NJ : John Wiley & Sons, [2006]
Online access available from:
Wiley Online Books    View Resource Record  


Description 1 online resource (xvii, 350 pages, 8 unnumbered pages of plates) : illustrations (some color)
Contents Tumor vasculature : a target for anticancer therapies / Dietmar W. Siemann -- Abnormal microvasculature and defective microcirculatory function in solid tumors / Peter Vaupel -- The role of microvasculature in metastasis formation / Oliver Stöltzing, Lee M. Ellis -- Development of agents that selectively disrupt tumor vasculature : a historical perspective / David J. Chaplin, Sally A. Hill -- Morphologic manifestations of vascular-disrupting agents in preclinical models / Mumtaz V. Rojiani, Amyn Rojiani -- Molecular recognition of the colchicine binding site as a design paradigm for the discovery and development of vascular disrupting agents / Kevin G. Pinney -- Combined modality approaches using vascular-disrupting agents / Wenyin Shi, Michael R. Horsman, Dietmar W. Siemann -- Vascular-targeting therapies and hyperthermia / Michael R. Horsman, Rumi Murata -- Flavones and xanthenones as vascular-disrupting agents / Bronwyn G. Siim, Bruce C. Baguley -- Targeting inside-out phospholipids on tumor blood vessels in pancreatic cancer / Adam W. Beck, Rolf Brekken, Philip E. Thorpe -- Cadherin antagonists as vascular-targeting agents / Orest Blaschuk, Tracey M. Rowlands -- Alphastatin : a pluripotent inhibitor of activated endothelial cells / Carolyn A. Staton, Claire Lewis -- Cationic lipid complexes to target tumor endothelium / Uwe Michaelis, Michael Teifel -- Development of vascular-targeting cancer gene therapy / Graeme J. Dougherty, Peter D. Davis, Shona T. Dougherty -- Vascular-disrupting strategies combined with bacterial spores targeting hypoxic regions of solid tumors / G-One Ahn, J. Martin Brown -- Imaging the effects of vascular-targeting agents / Susan M. Galbraith -- Clinical progress in tumor vasculature-disrupting therapies / Andrew M. Gaya, Gordon J.S. Rustin -- Use of vascular-disrupting agents in non-oncology indications / Joseph C. Randall, Scott Young
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Neoplasms -- drug therapy.
Angiogenesis Inhibitors -- therapeutic use.
Blood Vessels -- drug effects.
Drug Delivery Systems.
Endothelial Cells -- drug effects.
Neovascularization, Pathologic.
Blood-vessels -- Effect of drugs on.
Cancer -- Chemotherapy.
Neovascularization inhibitors.
Genetic Therapy -- methods.
Form Electronic book
Author Siemann, Dietmar W.
ISBN (alk. paper)
(alk. paper)