| Description |
1 online resource (ix, 419 pages) : illustrations |
| Series |
Drugs and the pharmaceutical sciences ; v. 167 |
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Drugs and the pharmaceutical sciences ; v. 167.
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| Contents |
Front cover; Preface; Contents; Contributors; Chapter 1. Historical and Emerging Themes; Chapter 2. Endotoxin Relevance and Control Overview; Chapter 3. Fever and the Host Response; Chapter 4. Endotoxin Structure, Function, and Activity; Chapter 5. Descent of Limulus: Arthropoda and the New Biology; Chapter 6. Microbial Biodiversity and Lipopolysaccharide Heterogeneity: from Static to Dynamic Models; Chapter 7. Nonendotoxin Microbial Pyrogens: Lesser Endotoxins and Superantigens; Chapter 8. Risk Assessment in Parenteral Manufacture; Chapter 9. Endotoxin as a Standard |
| Summary |
This source expertly examines the discovery, biological structure, control, and continued clarification of endotoxin from a parenteral manufacturing perspective, with in-depth discussion of state-of-the-art technologies involving Limulus amebocyte lysate (LAL) such as assay development, automation, depyrogenation. Completely revised and expanded, this Third Edition contains the knowledge necessary to apply endotoxin testing in the increasingly complex pharmaceutical environment, featuring sections detailing the latest information regarding clinical advances, regulation st |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. http://purl.oclc.org/DLF/benchrepro0212 MiAaHDL |
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Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL |
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Print version record |
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digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL |
| Subject |
Endotoxins -- Analysis.
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Pyrogens -- Analysis
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Limulus test.
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Drugs -- Microbiology.
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Endotoxins -- analysis
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Pyrogens -- analysis
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Drug Contamination
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Infusions, Parenteral -- standards
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Limulus Test
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MEDICAL -- Toxicology.
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Drugs -- Microbiology
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Endotoxins -- Analysis
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Limulus test
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Pyrogens -- Analysis
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| Form |
Electronic book
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| Author |
Williams, Kevin L.
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| ISBN |
9781420020595 |
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1420020595 |
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