Introduction; IL-22 and IL-17: Common and different properties; Other sources of IL-17: Invariant natural killer T cells; Contributions of IL-22 to Th17 responses: Repairing and protecting peripheral tissues; Retinoic acid in mucosal immune-regulation; IL-25, another promoter of allergy; Critical role of IL-17 in experimental arthritis; Dual role of IL-17 in allergic asthma; Contribution of IL-17 to the pulmonary inflammatory response; The role of IL-17 in experimental autoimmune myocarditis; Th17 cells in organ transplantation; Is IL-17 required to control tuberculosis?
Summary
Describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. This book reviews the mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man. It addresses the role of Th17 in infectious conditions