A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism
A superfamily of hundreds of closely related HEMEPROTEINS found throughout the phylogenetic spectrum, from animals, plants, fungi, to bacteria. They include numerous complex monooxygenases (MIXED FUNCTION OXYGENASES). In animals, these P-450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs (BIOTRANSFORMATION). They are classified, according to their sequence similarities rather than functions, into CYP gene families (>40% homology) and subfamilies (>59% homology). For example, enzymes from the CYP1, CYP2, and CYP3 gene families are responsible for most drug metabolism
Enzymes -- Programmed instruction. : Enzyme kinetics : a learning program for students of the biological and medical sciences / Halvor N. Christensen and Graham A. Palmer
Enzymes -- Specifications. : Specification for the identity and purity of some enzymes and certain other substances
1972
1
Enzymes -- Stability. : Stability and stabilization of biocatalysts : proceedings of an international symposium / organized under auspices of the Working Party on Applied Biocatalysis of the European Federation of Biotechnology, the University of Cordoba, Spain, and the Spanish Society of Biotechnology, Cordoba, Spain, April 19-22, 1998 ; edited by A. Ballesteros [and others]
1998
1
Enzymes -- Stability -- Congresses : Stability and stabilization of biocatalysts : proceedings of an international symposium / organized under auspices of the Working Party on Applied Biocatalysis of the European Federation of Biotechnology, the University of Cordoba, Spain, and the Spanish Society of Biotechnology, Cordoba, Spain, April 19-22, 1998 ; edited by A. Ballesteros [and others]
1998
1
Enzymes -- standards. : Specification for the identity and purity of some enzymes and certain other substances
Enzymes -- Therapeutic use -- Congresses. : Advances in the treatment of inborn errors of metabolism : the proceedings of the 2nd Clinical Research Centre symposium held in September 1981 / edited by M. d'A. Crawfurd, Dorothy A. Gibbs, R.W.E. Watts
Enzymes -- Toxicology. : Toxicological evaluation of some enzymes, modified starches and certain other substances / The evaluations contained in this publication were prepared by the Joint FAO/WHO Expert Committee on Food Additives, which met in Rome, 16-24 June 1971
1972
1
Enzyminhibitor : Inhibitors of protein kinases and protein phosphataes / contributors, D.R. Alexander [and others] ; editors, Lorenzo A. Pinna and Patricia T.W. Cohen
