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Title Cysteine proteases of pathogenic organisms / edited by Mark W. Robinson, John P. Dalton
Published New York : Springer Science+Business Media ; Austin, Tex. : Landes Bioscience, ©2011


Description 1 online resource (xix, 226 pages) : illustrations
Series Advances in experimental medicine and biology ; v. 712
Advances in experimental medicine and biology ; v. 712.
Contents Papain-like proteases of staphylococcus aureus -- Lysine specific gingipain of Porphyromonas gingivalis: importance to pathogenicity and potential strategies for inhibition -- Falcipains and other cysteine proteases of malaria parasites -- Cathepsin proteases in Toxoplasma gondii -- Entamoeba Histolytica cathepsin-like enzymes -- Cysteine peptidases of kinetoplastid parasites -- Cruzain: the path from target validation to the clinic -- Phylogeny, structure and function of trematode cysteine proteases, with particular emphasis on the Fasciola hepatica cathepsin L family -- Cathepsins B1 and B2 of Trichobilharzia spp., bird schistosomes causing cercarial dermatitis -- Proteases in blood feeding nematodes and their potential as vaccine candidates -- Cysteine proteases from bloodfeeding arthropod ectoparasites -- How pathogen derived cysteine proteases modulate host immune responses -- Cystatins of parasitic organisms
Summary Cysteine proteases expressed by pathogenic organisms play key roles in virulence including host entry, feeding and suppression of host immune responses. This book gives comprehensive coverage to all aspects of pathogen cysteine proteases and brings together numerous scientific advances which have been made over many years. Thus, the biochemistry, molecular biology and structure function relationships of these important pathogen enzymes are covered in detail. Written by leading researchers from Europe, Australia and North America, this book is essential reading for students and professionals interested in human medicine and infectious disease research --Provided by publisher
Analysis geneeskunde
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes Print version record
Subject Cysteine proteinases -- Pathophysiology
Microbial enzymes.
Pathogenic microorganisms.
Cysteine Proteases -- chemistry
Bacteria -- enzymology
Cysteine Proteases -- immunology
Eukaryota -- enzymology
Viruses -- enzymology
Microbial enzymes
Pathogenic microorganisms
Form Electronic book
Author Robinson, Mark W. (Mark William), 1977-
Dalton, J. P. (John Pius), 1958-
ISBN 9781441984142