| Description |
1 online resource (l, 888 pages) : illustrations, portraits |
| Contents |
An introduction to the extracellular matrix molecules and their importance in pathobiology and signaling / Achilleas Theocharis [and others] -- Insights into the function of glycans / Paraskevi Heldin -- Proteoglycans : structure, pathobiology, and signaling / Liliana Schaefer -- ECM cell surface receptors / Donald Gullberg -- Extracellular proteinases / Jan-Olof Winberg -- Collagen : not just mechanics, for the high degree of connectivity grounded on the apparently simple triple helix / Ruggero Tenni -- Emerging aspects in extracellular matrix pathobiology / Achilleas Theocharis -- Targeting tumor microenvironment at the ECM level / Nikos K. Karamanos |
| Summary |
Over the last decades cell biology and biological chemistry have increasingly turned their attention to the space between cells and revealed an elaborate network of macromolecules essential for structural support, cell migration, adhesion and signaling. This comprehensive handbook of the extracellular matrix is organized into seven thematic sections, giving an overview of the current state of knowledge of matrix components (structure and function), their roles in health and disease (matrix pathobiology) as well as new concepts of pharmacological targeting |
| Bibliography |
Includes bibliographical references and index |
| Notes |
In English |
|
Online resource; title from PDF title page (de Gruyter, viewed November 6, 2018) |
| Subject |
Extracellular matrix.
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Cellular signal transduction.
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Extracellular Matrix -- pathology
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Signal Transduction -- physiology
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Extracellular Matrix
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Signal Transduction
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MEDICAL -- Histology.
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Extracellular matrix
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Cellular signal transduction
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Pathophysiologie
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Signaltransduktion
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Extrazelluläre Matrix
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| Form |
Electronic book
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| Author |
Karamanos, Nikos K., editor.
|
| ISBN |
9783110258776 |
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3110258773 |
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9783110258776 |
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