| Description |
1 online resource (xii, 143 pages) : illustrations |
| Series |
Advances in anatomy, embryology and cell biology ; 210 |
|
Advances in anatomy, embryology, and cell biology ; 210.
|
| Contents |
Factors limiting motor recovery after facial nerve injury -- Attempts to improve axonal pathfinding and quality of target reinnervation |
| Summary |
Using a combined morpho-functional approach the author found that polyinnervation of the neuro-muscular juction (NMJ) is the critical factor for recovery of function after transection and suture of the facial nerve. Since polyinnervation is activity-dependent and can be manipulated, the author tried to design a clinically feasible therapy by electrical stimulation or by soft tissue massage. First, electrical stimulation was applied to the transected facial nerve or to paralysed facial muscles. Both procedures did not improve vibrissal motor performance (video-based motion analysis of whisking), failed to diminish polyinnervation and even reduced the number of innervated NMJ to one fifth of normal values. In contrast, gentle stroking of the paralysed vibrissal muscles by hand resulted in full recovery of whisking. This manual stimulation depends on intact sensory supply of the denervated muscle targets and is also effective after hypoglossal-facial anastomosis, after interpositional nerve grafting, when applied to the orbicularis oculi muscle and after transection and suture of the hypoglossal nerve. From these results the author concludes that manual stimulation is a non-invasive procedure with immediate potential for clinical rehabilitation following facial nerve reconstruction |
| Analysis |
biomedische wetenschappen |
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biomedicine |
|
neurowetenschap |
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neuroscience |
|
Medicine (General) |
|
Geneeskunde (algemeen) |
| Bibliography |
Includes bibliographical references (pages 121-140) and index |
| Notes |
Print version record |
| Subject |
Facial paralysis.
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Face -- Muscles.
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Outcome assessment (Medical care)
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Facial Paralysis -- therapy
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Electric Stimulation Therapy -- methods
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Massage -- methods
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Facial Muscles
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Facial Nerve Injuries
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Outcome Assessment, Health Care
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Facial Paralysis
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Outcome and Process Assessment, Health Care
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Treatment Outcome
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HEALTH & FITNESS -- Diseases -- Nervous System (incl. Brain)
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MEDICAL -- Neurology.
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Outcome assessment (Medical care)
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Face -- Muscles
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Facial paralysis
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| Form |
Electronic book
|
| ISBN |
9783642181207 |
|
3642181201 |
|
3642181198 |
|
9783642181191 |
|
