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Book Cover
Author Nógrádi, Antal

Title Transplantation of neural tissue into the spinal cord / Antal Nógrádi
Edition 2nd ed
Published Georgetown, Tex. : Landes Bioscience :, ©2006


Description 1 online resource (150 pages) : illustrations
Series Neuroscience intelligence unit
Neuroscience intelligence unit.
Contents Anatomy and physiology of the spinal cord / Antal Nógrádi and Gerta Vrbová -- Recovery of function after spinal cord injury / Gavin Clowry and Urszula Slawinska -- Recovery of lost spinal cord function by facilitating the spinal cord circuits below the lesion / Urszula Slawinska -- Encouraging regeneration of host neurones: the use of peripheral nerve bridges, glial cells or biomaterials / Antal Nógrádi -- Encouraging regeneration of host neurons: transplantation of neural tissues into the injured spinal cord grafts of embryonic neural tissue / Gerta Vrbová -- Replacement of specific neuronal populations in the spinal cord / Antal Nógrádi -- Replacement of specific populations of cells: glial cell transplantation into the spinal cord / Antal Nógrádi
Summary The book gives an account of results obtained from experiments where grafts of neuronal, glial and other tissues as well as artificial materials were placed into the spinal cord. It attempts to evaluate the contributions made by these studies to our understanding of basic neurobiologies questions. These include factors that regulate neuronal growth during development as well as regenera­ tion following injury to the nervous system. The model of neural transplanta­ tion is also useful for the study of cell-to-cell interactions, and this applies to interactions between glial cells and neurones, between various populations of neuronal cells and finally between axons and skeletal muscle fibres. The mecha­ nisms involved in the establishment of specific synaptic connections between neurones can also be investigated in this experimental paradigm. Important in­ formation regarding this issue was also obtained on systems other than the spinal cord, i. e. the cerebellum, hippocampus and striatum. Although such in­ formation of precise connections between the host and the grafted embryonic tissue is still lacking in the spinal cord, there is much information on the re­ sponse of the host nervous system to the grafted embryonic tissue, and that of the graft to its new host environment. It appears that embryonic grafts are able to induce repair processes follow­ ing injury to the nervous system
Analysis neurologie
biomedische wetenschappen
Medicine (General)
Geneeskunde (algemeen)
Bibliography Includes bibliographical references and index
Notes English
Print version record
Subject Fetal nerve tissue -- Transplantation
Spinal cord -- Regeneration.
Nervous system -- Regeneration.
Nerve Tissue -- transplantation
Spinal Cord Injuries -- surgery
Nerve Regeneration
MEDICAL -- Surgery -- Neurosurgery.
Sciences de la vie.
Nervous system -- Regeneration
Fetal nerve tissue -- Transplantation
Spinal cord -- Regeneration
Form Electronic book
ISBN 9780387326337
OTHER TI Transplantation of neural tissue into the spinal cord