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Title Renal fibrosis / volume editors, Mohammed S. Razzaque, Takashi Taguchi
Published Basel ; New York : Karger, 2003


Description 1 online resource (x, 211 pages) : illustrations (some color)
Series Contributions to nephrology, 0302-5144 ; v. 139
Contributions to nephrology ; v. 139. 0302-5144
Contents Preface -- Foreword -- Factors That Influence and Contribute to the Regulation of Fibrosis -- Disturbance of Syncytial Cell Function in Glomerular Mesangial Cells Involved in the Progressive Glomerular Diseases -- Proteinuria and Tubulointerstitial Injury: The Causative Factors for the Progression of Renal Diseases -- Molecular Mechanism of Cell Injury -- Role of TGF- in the Progression of Renal Fibrosis -- Chemokines in Renal Fibrosis -- Pathological Significance of Renal Expression of NF- B
Oxidant Stress and Regulation of Chemokines in the Development of Renal Interstitial Fibrosis -- Role of Myofibroblasts in Progressive Renal Diseases -- Regulation of Renal Extracellular Matrix Metabolism -- Implication of Apoptosis in Progression of Renal Diseases -- Factors Regulating the Progression of Hypertensive Nephrosclerosis -- Pathogenesis and Molecular Mechanisms of Chronic Allograft Nephropathy -- Author Index -- Subject Index
Summary This publication provides a synopsis of the rapid progress made in the field of renal cell biology during the last decade, progress which has resulted in a better conceptual understanding of the cellular and molecular mechanisms of fibrotic renal disease. These developments have provided new therapeutic choices and led to the discovery of gene-based therapeutic options. The topics covered in this book have been carefully selected from the immense number of aspects of the disease to provide essential information on the molecular basis of renal fibrosis. Individual chapters discuss topics such as proteinuria and tubulointerstitial injury, the roles and regulation of TGF-beta, chemokines, oxidant stress, matrix remodeling, significance of renal expression of NF-kappa, and the potential impact of cell death in renal fibrosis. Written so as to present the complex information as simply as possible, this publication will be a very useful tool for general health professionals involved in the fields of immunology and cell biology, as well as for clinicians and researchers within the fields of nephrology, pathology and matrix biology
Bibliography Includes bibliographical references and indexes
Notes Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL
Print version record
digitized 2010 HathiTrust Digital Library committed to preserve pda MiAaHDL
Subject Kidneys -- Fibrosis -- Molecular aspects
Kidney Diseases -- physiopathology
MEDICAL -- Nephrology.
Maladies du rein -- physiopathologie.
Rein -- Fibrose -- Aspect mol├ęculaire.
Form Electronic book
Author Razzaque, Mohammed S
Taguchi, Takashi
ISBN 0585471703