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Title Alzheimer's disease and frontotemporal dementia : methods and protocols / edited by Erik D. Roberson
Published New York : Humana Press, [2011]


Location Call no. Vol. Availability
 W'PONDS  616.83 Rob/Ada  AVAILABLE
Description x, 277 pages : illustrations (some color) ; 27 cm
Series Methods in molecular biology, 1064-3745 ; 670
Springer protocols
Methods in molecular biology (Clifton, N.J.) ; v. 670. 1064-3745
Springer protocols (Series)
Contents Contemporary approaches to Alzheimer's disease and frontotemporal dementia / Erik D. Roberson -- Preparing synthetic A[beta] in different aggregation states / W. Blaine Stine ... [et al.] -- Isolation of low-n amyloid [beta]-protein oligomers from cultured cells, CSF, and brain / Ganesh M. Shankar ... [et al.] -- Detecting A[beta]*56 oligomers in brain tissues / Mathew A. Sherman and Sylvain E. Lesné -- Assessing A[beta] aggregation state by atomic force microscopy / Justin Legleiter -- Measuring APP carboxy-terminal fragments / Luke A. Esposito -- Detection of APP intracellular domain in brain tissue / Sanjay W. Pimplikar and Anupama Suryanarayana -- Cell-based assays for regulators of tau biology / Umesh K. Jinwal and Chad A. Dickey -- Split GFP complementation assay for quantitative measurement of tau aggregation in situ / Wanjoo Chun, Geoffrey S. Waldo, and Gail V.W. Johnson -- Apolipoprotein E expression and purification / Yvonne Newhouse and Karl H. Weisgraber -- A[beta] toxicity in primary cultured neurons / Adriana Ferreira ... [et al.] -- Manipulation of gene expression in the central nervous system with lentiviral vectors / Binggui Sun and Li Gan -- Selecting a mouse model of Alzheimer's disease / Jeannie Chin -- Monitoring spatial learning and memory in Alzheimer's disease mouse models using the Morris water maze / Kimberly Scearce-Levie -- Step-by-step in situ hybridization method for localizing gene expression changes in the brain / Jorge J. Palop, Erik D. Roberson, and Inma Cobos -- Real-time visualization of axonal transport in neurons / Yasuko Osakada and Bianxiao Cui -- Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease : depletion of calcium-dependent proteins and inhibitory hippocampal remodeling / Jorge J. Palop, Lennart Mucke, and Erik D. Roberson -- Epigenetic changes in the brain : measuring global histone modifications / Gavin Rumbaugh and Courtney A. Miller
Bibliography Includes bibliographical references and index
Subject Dementia.
Alzheimer's disease.
Alzheimer Disease.
Frontotemporal Dementia.
Models, Neurological.
Author Roberson, Erik D.
LC no. 2010938365
ISBN 9781607617433 (hbk. : alk. paper)
1607617439 (hbk. : alk. paper)
9781607617440 e-ISBN
1607617447 e-ISBN