| Description |
1 online resource (viii, 252 pages) |
| Contents |
Chapter 1 Metabolism and distribution of -hydroxybutyrate in the brain -- chapter 2 The -hydroxybutyrate receptor in the brain -- chapter 3 Part of the pharmacological actions of -hydroxybutyrate are mediated by GABA B receptors -- chapter 4 Membrane transport of -hydroxybutyrate -- chapter 5 Action of -hydroxybutyrate on neuronal excitability and underlying membrane conductances -- chapter 6 Regulation of central dopamine by -hydroxybutyrate -- chapter 8 -Hydroxybutyrate and absence seizure activity -- chapter 9 Behavioral pharmacology of -hydroxybutyrate -- chapter 10 Therapeutic uses of -hydroxybutyrate -- chapter 11 Abuse potential and toxicology of -hydroxybutyrate -- chapter 12 4-Hydroxybutyric aciduria -- chapter 13 -Hydroxybutyrate and oxidative stress -- chapter 14 The role of -hydroxybutyrate in brain function |
| Summary |
Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state and from its use in general anaesthesia in human subjects. It has been found to be a naturally-occurring compound in the brain, a metabolite of GABA, the emerging ubiquitous inhibitory neurotransmitter. This has opened up a completely new line of research in an effort to establish a function for GHB. Gamma-Hydroxybutyrate: Pharmacological and Functional Aspects has brought together the combined expertise of many of the leading authorities on the biochemistry |
| Notes |
Title from e-book title screen (viewed October 15, 2007) |
| Bibliography |
Includes bibliographical references and index |
| Subject |
GABA.
|
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Neurochemistry.
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GABA -- Therapeutic use
|
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Sodium Oxybate -- metabolism
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gamma-Aminobutyric Acid
|
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Neurochemistry
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Brain -- metabolism
|
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Sodium Oxybate -- therapeutic use
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MEDICAL -- Pain Medicine.
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MEDICAL -- Psychiatry -- Psychopharmacology.
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GABA
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GABA -- Therapeutic use
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Neurochemistry
|
| Form |
Electronic book
|
| Author |
Tunnicliff, Godfrey
|
|
Cash, Christopher D
|
| LC no. |
2009659001 |
| ISBN |
0203300998 |
|
9780203300992 |
|
9786610022076 |
|
6610022070 |
|
9780415284998 |
|
0415284996 |
|
9780429219184 |
|
0429219180 |
|
