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Gene, nf 2 -- See Genes, Neurofibromatosis 2


Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2
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Gene, nf2 -- See Genes, Neurofibromatosis 2


Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2
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Gene, Onco-Suppressor -- See Genes, Tumor Suppressor


Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible
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Gene Ontologies -- See Gene Ontology


Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium
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Gene Ontology. : The gene ontology handbook / edited by Christophe Dessimoz, Nives Škunca  2017 1
 

Gene Ontology Project -- See Gene Ontology


Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium
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Gene Ontology Projects -- See Gene Ontology


Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium
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  Gene Order -- 2 Related Subjects   2
 

Gene, Overlapping -- See Genes, Overlapping


Genes whose nucleotide sequences overlap to some degree. The overlapped sequences may involve structural or regulatory genes of eukaryotic or prokaryotic cells
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Gene, p53 -- See Genes, p53


Tumor suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53
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Gene (Papua New Guinean people) -- See Gende (Papua New Guinean people)


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Gene, Plant -- See Genes, Plant


The functional hereditary units of PLANTS
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Gene, Pleiotropic -- See Genetic Pleiotropy


A phenomenon in which multiple and diverse phenotypic outcomes are influenced by a single gene (or single gene product.)
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Gene Pool -- See Also Founder Effect


A phenomenon that is observed when a small subgroup of a larger POPULATION establishes itself as a separate and isolated entity. The subgroup's GENE POOL carries only a fraction of the genetic diversity of the parental population resulting in an increased frequency of certain diseases in the subgroup, especially those diseases known to be autosomal recessive
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Gene Pool. : Livestock / Committee on Managing Global Genetic Resources: Agricultural Imperatives, Board on Agriculture, National Research Council  1993 1
 

Gene Pools -- See Gene Pool


The total genetic information possessed by the reproductive members of a POPULATION of sexually reproducing organisms
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Gene probes -- See DNA probes


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Gene Probes, Conserved -- See DNA Probes


Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections
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Gene Probes, DNA -- See DNA Probes


Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections
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Gene Product, Bacterial -- See Bacterial Proteins


Proteins found in any species of bacterium
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Gene Product, Ob -- See Leptin


A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage
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Gene Product, Obese -- See Leptin


A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in regulation of food intake, energy balance, and fat storage
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Gene Products, Bacterial -- See Bacterial Proteins


Proteins found in any species of bacterium
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Gene Products, Fungal -- See Fungal Proteins


Proteins found in any species of fungus
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  Gene Products, pol -- 2 Related Subjects   2
 

Gene Products, Protein -- See Proteins


Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein
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Gene Products, ras -- See ras Proteins


Small, monomeric GTP-binding proteins encoded by ras genes (GENES, RAS). The protooncogene-derived protein, PROTO-ONCOGENE PROTEIN P21(RAS), plays a role in normal cellular growth, differentiation and development. The oncogene-derived protein (ONCOGENE PROTEIN P21(RAS)) can play a role in aberrant cellular regulation during neoplastic cell transformation (CELL TRANSFORMATION, NEOPLASTIC). This enzyme was formerly listed as EC 3.6.1.47
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Gene Products, RNA -- See RNA


A polynucleotide consisting essentially of chains with a repeating backbone of phosphate and ribose units to which nitrogenous bases are attached. RNA is unique among biological macromolecules in that it can encode genetic information, serve as an abundant structural component of cells, and also possesses catalytic activity. (Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)
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Gene Products, Viral -- See Viral Proteins


Proteins found in any species of virus
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Gene Protein, Bacterial -- See Bacterial Proteins


Proteins found in any species of bacterium
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Gene Proteins -- See Proteins


Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein
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Gene Proteins, Bacterial -- See Bacterial Proteins


Proteins found in any species of bacterium
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Gene Proteins, Fungal -- See Fungal Proteins


Proteins found in any species of fungus
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  Gene rearrangement -- 3 Related Subjects   3
Gene Rearrangement.   2
 

Gene Rearrangement, T-Lymphocyte -- See Also Genes, T-Cell Receptor


DNA sequences, in cells of the T-lymphocyte lineage, that code for T-cell receptors. The TcR genes are formed by somatic rearrangement (see GENE REARRANGEMENT, T-LYMPHOCYTE and its children) of germline gene segments, and resemble Ig genes in their mechanisms of diversity generation and expression
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Gene Rearrangements -- See Gene Rearrangement


The ordered rearrangement of gene regions by DNA recombination such as that which occurs normally during development
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Gene regulation -- See Genetic regulation


Here are entered works on the control of the type and rate of cellular processes by regulation of the activity of specific genes controlling individual biochemical reactions. Works on the various mechanisms of cellular control such as structural control, biochemical control, cell differentiation, etc., are entered under Cellular control mechanisms
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Gene regulation. : Schaum's Biology Problem 10.8: Histone Role in Transcription / Ella Ingram  c2013 1
 

Gene Regulatory Network -- See Gene Regulatory Networks


Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations
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Gene Regulatory Networks -- See Also Gene Expression Regulation


Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation
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Gene regulatory networks.   18
Gene regulatory networks -- Computer simulation   2
Gene Regulatory Networks -- drug effects : Bacterial signal transduction : networks and drug targets / edited by Ryutaro Utsumi  2008 1
Gene Regulatory Networks -- genetics   2
Gene regulatory networks -- Mathematical models : Analysis of deterministic cyclic gene regulatory network models with delays / Mehmet Eren Ahsen, Hitay Özbay, Silviu-Iulian Niculescu  2015 1
Gene regulatory networks -- Mathematical models -- Handbooks, manuals, etc : Handbook of research on computational methodologies in gene regulatory networks / [edited by] Sanjoy Das ... [et al.]  c2010 1
Gene Regulatory Networks -- physiology   4
 

Gene, Reiterated -- See Multigene Family


A set of genes descended by duplication and variation from some ancestral gene. Such genes may be clustered together on the same chromosome or dispersed on different chromosomes. Examples of multigene families include those that encode the hemoglobins, immunoglobulins, histocompatibility antigens, actins, tubulins, keratins, collagens, heat shock proteins, salivary glue proteins, chorion proteins, cuticle proteins, yolk proteins, and phaseolins, as well as histones, ribosomal RNA, and transfer RNA genes. The latter three are examples of reiterated genes, where hundreds of identical genes are present in a tandem array. (King & Stanfield, A Dictionary of Genetics, 4th ed)
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Gene-Related Peptide, Calcitonin -- See Calcitonin Gene-Related Peptide


A 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. The peptide produces multiple biological effects and has both circulatory and neurotransmitter modes of action. In particular, it is a potent endogenous vasodilator
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