Limit search to available items
Nearby Subjects are:
Result Page   Prev Next
Add Marked to Bag Add All On Page Add Marked to My Lists
Mark   Year Entries
 

Gene Knockout Techniques -- See Also Mice, Knockout


Strains of mice in which certain GENES of their GENOMES have been disrupted, or "knocked-out". To produce knockouts, using RECOMBINANT DNA technology, the normal DNA sequence of the gene being studied is altered to prevent synthesis of a normal gene product. Cloned cells in which this DNA alteration is successful are then injected into mouse EMBRYOS to produce chimeric mice. The chimeric mice are then bred to yield a strain in which all the cells of the mouse contain the disrupted gene. Knockout mice are used as EXPERIMENTAL ANIMAL MODELS for diseases (DISEASE MODELS, ANIMAL) and to clarify the functions of the genes
  1
 

Gene, L-myc -- See Genes, myc


Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8
  1
 

Gene, Lac -- See Lac Operon


The genetic unit consisting of three structural genes, an operator and a regulatory gene. The regulatory gene controls the synthesis of the three structural genes: BETA-GALACTOSIDASE and beta-galactoside permease (involved with the metabolism of lactose), and beta-thiogalactoside acetyltransferase
  1
 

Gene, LacZ -- See Lac Operon


The genetic unit consisting of three structural genes, an operator and a regulatory gene. The regulatory gene controls the synthesis of the three structural genes: BETA-GALACTOSIDASE and beta-galactoside permease (involved with the metabolism of lactose), and beta-thiogalactoside acetyltransferase
  1
  Gene Libraries -- 2 Related Subjects   2
Gene libraries.   18
Gene libraries -- Laboratory manuals.   5
  Gene Library -- 3 Related Subjects   3
Gene Library.   14
  Gene Mapping -- 4 Related Subjects   4
Gene mapping.   91
Gene mapping -- Atlases   2
Gene mapping -- Automation.   2
Gene mapping -- Congresses. : Bovine genome : mapping and trypanotolerance : proceedings of a workshop held at ILRAD, Nairobi, Kenya, 9-11 April 1991 / edited by A.J. Teale  1991 1
Gene mapping -- Data processing   6
Gene mapping -- Forecasting   2
Gene mapping -- History -- 20th century -- Congresses : Classical genetic research and its legacy : the mapping cultures of twentieth-century genetics / edited by Hans-Jörg Rheinberger and Jean-Paul Gaudillière  2004 1
Gene mapping -- Laboratory manuals   11
Gene mapping -- Mathematical models   2
Gene mapping -- Methodology : Gene mapping, discovery, and expression : methods and protocols / edited by Minou Bina  2006 1
Gene mapping -- Periodicals   9
Gene mapping -- Social aspects : The McKinsey mind : understanding and implementing the problem-solving tools and management techniques of the world's top strategic consulting firm / Ethan M. Rasiel and Paul N. Friga  2016 1
Gene mapping -- Statistical methods.   6
Gene mapping -- Statistical methods -- Congresses   10
Gene mapping -- Technique. : Genetic analysis of complex diseases / [edited by] Jonathan L. Haines, Margaret Pericak-Vance  2006 1
Gene mapping -- Technological innovations   2
 

Gene Mappings -- See Chromosome Mapping


Any method used for determining the location of and relative distances between genes on a chromosome
  1
 

Gene, Metastasis Suppressor -- See Genes, Tumor Suppressor


Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible
  1
 

Gene, Mitochondrial -- See Genes, Mitochondrial


Genes that are located on the MITOCHONDRIAL DNA. Mitochondrial inheritance is often referred to as maternal inheritance but should be differentiated from maternal inheritance that is transmitted chromosomally
  1
 

Gene Module -- See Gene Regulatory Networks


Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations
  1
  Gene modules -- 2 Related Subjects   2
 

Gene, myc -- See Genes, myc


Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8
  1
 

Gene, N-myc -- See Genes, myc


Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8
  1
 

Gene, Neoplasm -- See Genes, Neoplasm


Genes whose abnormal expression, or MUTATION are associated with the development, growth, or progression of NEOPLASMS
  1
 

Gene Network -- See Gene Regulatory Networks


Interacting DNA-encoded regulatory subsystems in the GENOME that coordinate input from activator and repressor TRANSCRIPTION FACTORS during development, cell differentiation, or in response to environmental cues. The networks function to ultimately specify expression of particular sets of GENES for specific conditions, times, or locations
  1
  Gene networks -- 2 Related Subjects   2
 

Gene, Neurofibromatosis 2 -- See Genes, Neurofibromatosis 2


Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2
  1
 

Gene, nf 2 -- See Genes, Neurofibromatosis 2


Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2
  1
 

Gene, nf2 -- See Genes, Neurofibromatosis 2


Tumor suppressor genes located on the long arm of human chromosome 22. Mutation or loss of these genes causes NEUROFIBROMATOSIS 2
  1
 

Gene, Onco-Suppressor -- See Genes, Tumor Suppressor


Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible
  1
 

Gene Ontologies -- See Gene Ontology


Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium
  1
Gene Ontology. : The gene ontology handbook / edited by Christophe Dessimoz, Nives Škunca  2017 1
 

Gene Ontology Project -- See Gene Ontology


Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium
  1
 

Gene Ontology Projects -- See Gene Ontology


Sets of structured vocabularies used for describing and categorizing genes, and gene products by their molecular function, involvement in biological processes, and cellular location. These vocabularies and their associations to genes and gene products (Gene Ontology annotations) are generated and curated by the Gene Ontology Consortium
  1
  Gene Order -- 2 Related Subjects   2
Gene Order : Mapping genetic interactions / edited by Franco Joseph Vizeacoumar and Andrew Freywald  2021 1
 

Gene, Overlapping -- See Genes, Overlapping


Genes whose nucleotide sequences overlap to some degree. The overlapped sequences may involve structural or regulatory genes of eukaryotic or prokaryotic cells
  1
 

Gene, p53 -- See Genes, p53


Tumor suppressor genes located on the short arm of human chromosome 17 and coding for the phosphoprotein p53
  1
 

Gene (Papua New Guinean people) -- See Gende (Papua New Guinean people)


  1
 

Gene, Plant -- See Genes, Plant


The functional hereditary units of PLANTS
  1
Add Marked to Bag Add All On Page Add Marked to My Lists
Result Page   Prev Next