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Title The gene ontology handbook / edited by Christophe Dessimoz, Nives Škunca
Published New York : Humana Press : SpringerOpen, [2017]
Online access available from:
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Description 1 online resource (xii, 305 pages) : illustrations (some color)
Series Methods in molecular biology, 1064-3745 ; 1446
Springer protocols
Methods in molecular biology (Clifton, N.J.) ; v. 1446. 1064-3745
Springer protocols (Series)
Contents Primer on Ontologies -- The Gene Ontology and the Meaning of Biological Function -- Primer on the Gene Ontology -- Best Practices in Manual Annotation with the Gene Ontology -- Computational Methods for Annotation Transfers from Sequence -- Text Mining to Support Gene Ontology Curation and Vice Versa -- How Does the Scientific Community Contribute to Gene Ontology? -- Evaluating Computational Gene Ontology Annotations -- Evaluating Functional Annotations of Enzymes Using the Gene Ontology -- Community-Based Evaluation of Computational Function Prediction -- Get GO!: Retrieving GO Data Using AmiGO, QuickGO, API, Files, and Tools -- Semantic Similarity in the Gene Ontology -- Gene-Category Analysis -- Gene Ontology: Pitfalls, Biases, and Remedies -- Visualizing GO Annotations -- A Gene Ontology Tutorial in Python -- Annotation Extensions -- The Evidence and Conclusion Ontology (ECO): Supporting GO Annotations -- Complementary Sources of Protein Functional Information: The Far Side of GO -- Integrating Bio-Ontologies and Controlled Clinical Terminologies: From Base Pairs to Bedside Phenotypes -- The Vision and Challenges of the Gene Ontology
Summary This book is open access under a CC BY 4.0 license. This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written for biologists and bioinformaticians, it covers the state-of-the-art of how GO annotations are made, how they are evaluated, and what sort of analyses can and cannot be done with the GO. In the spirit of the Methods in Molecular Biology book series, there is an emphasis throughout the chapters on providing practical guidance and troubleshooting advice. Authoritative and accessible, The Gene Ontology Handbook serves non-experts as well as seasoned GO users as a thorough guide to this powerful knowledge system
Bibliography Includes bibliographical references and index
Notes Online resource; title from PDF title page (SpringerLink, viewed November 14, 2016)
Subject Genetics -- Data processing -- Handbooks, manuals, etc.
Information theory in biology -- Handbooks, manuals, etc.
Ontologies (Information retrieval) -- Handbooks, manuals, etc.
Gene Ontology.
Computational Biology -- methods.
Genre/Form Handbooks and manuals.
Handbooks and manuals.
Form Electronic book
Author Dessimoz, Christophe, editor
Škunca, Nives, editor
LC no. 2016943478
ISBN 1493937413
149393743X (electronic bk.)
9781493937431 (electronic bk.)