Book Cover; Title; Copyright; Contents; List of contributors; List of figures; List of colour plates; List of tables; Preface; CHAPTER ONE Exploring intermediate phenotypes of psychosis; CHAPTER TWO The Maudsley Family Study of Psychosis " overview of clinical methodology and characteristics; CHAPTER THREE Auditory evoked potentials as genetic trait markers of schizophrenia; CHAPTER FOUR Are eye-movement abnormalities related to susceptibility genes for schizophrenia?; CHAPTER FIVE Neuropsychological impairments in patients with schizophrenia and their unaffected relatives
Summary
Psychotic disorders such as schizophrenia and bipolar disorder are known to be highly heritable. Despite decades of research, however, the genetic variations conferring susceptibility to these illnesses have yet to be identified. Such genetic variations most likely produce abnormalities of brain structure and function from which the clinical features of psychosis emerge. The Maudsley Family Study of Psychosis investigates the genetically produced markers of abnormal brain structure and function (intermediate phenotypes) which underlie the clinical syndrome of schizophrenia, and more recently
