| Description |
xx, 353 pages : illustrations (some color) ; 24 cm |
| Contents |
Ch. 1. DNA damage sensing and signaling / Jamie L. Wood and Junjie Chen -- Ch. 2. Base excision repair / Bo Hang -- Ch. 3. Nucleotide excision repair / Lei Li -- Ch. 4. DNA mismatch repair : biological functions and molecular mechanisms / Guo-Min Li -- Ch. 5. Mammalian homologous recombination repair and cancer intervention / Zhiyuan Shen and Jac A. Nickoloff -- Ch. 6. Role of non-homologous end joining in the repair of DNA double-strand breaks / Sandeep Burma, Benjamin Chen and David J. Chen -- Ch. 7. A DNA-damage response network of fanconi anemia and BRCA proteins / Rong Guo and Weidong Wang -- Ch. 8. Structure and function of DNA repair proteins : lesion recognition / Wei Yang -- Ch. 9. DNA damage tolerance and translesion synthesis / Fang Xu, Yingnian Yu and Wei Xiao -- Ch. 10. Nucleases in DNA repair, replication and recombination : flap endonuclease-1 as a paradigm / Purnima Singh and Binghui Shen |
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Ch. 11. Integrative genomics and epigenomics : application in cancer research / Maxwell P. Lee -- Ch. 12. Molecular epidemiology of DNA repair and cancer susceptibility - a review of population-based studies / Zhibin Hu, Li-E Wang and Qingyi Wei |
| Bibliography |
Includes bibliographical references and index |
| Subject |
DNA repair.
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Cancer -- Genetic aspects.
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Neoplasms -- etiology.
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Neoplasms -- genetics.
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DNA Damage -- genetics.
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DNA Repair -- genetics.
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DNA Repair-Deficiency Disorders.
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Genetic Predisposition to Disease.
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| Author |
Wei, Qingyi.
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Li, Lei, Dr.
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Chen, David, Dr.
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| LC no. |
2006050159 |
| ISBN |
9789812700148 cased |
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9812700145 cased |
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