| Description |
1 online resource (218 pages) |
| Series |
Maudsley monograph, 0076-5465 ; no. 50 |
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Maudsley monographs ; no. 50
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| Contents |
Exploring intermediate phenotypes of psychosis / Colm McDonald, Robin Murray -- The Maudsley family study of psychosis: overview of clinical methodology and characteristics / Colm McDonald -- Auditory evoked potentials as genetic trait markers of schizophrenia / Ian Williams, Sophia Frangou, and Elvira Bramon -- Are eye movement abnormalities related to susceptibility genes for schizophrenia? / James MacCabe, Jolanta Zanelli -- Neuropsychological impairments in patients with schizophrenia and their unaffected relatives / Timothea Toulopoulou, Francesca Filbey, and Eugenia Kravariti -- Neurological abnormalities in patients with schizophrenia from singly and multiply affected families and their relatives / Paola Dazzan and Timothy Griffiths -- Structural brain deviations in schizophrenia and bipolar disorder: to what extent are they genetically mediated? / Colm McDonald -- Summary and implications / Colm McDonald |
| Summary |
Psychotic disorders such as schizophrenia and bipolar disorder are known to be highly heritable. Despite decades of research, however, the genetic variations conferring susceptibility to these illnesses have yet to be identified. Such genetic variations most likely produce abnormalities of brain structure and function from which the clinical features of psychosis emerge. The Maudsley Family Study of Psychosis investigates the genetically produced markers of abnormal brain structure and function (?intermediate phenotypes?) which underlie the clinical syndrome of schizophrenia, and more recently |
| Bibliography |
Includes bibliographical references and index |
| Notes |
Restricted: Printing from this resource is governed by The Legal Deposit Libraries (Non-Print Works) Regulations (UK) and UK copyright law currently in force. WlAbNL |
|
Print version record |
| Subject |
Schizophrenia -- genetics.
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Family.
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Genetic Predisposition to Disease -- genetics.
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Psychotic Disorders -- genetics.
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Genetic markers.
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Manic-depressive illness -- Genetic aspects
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Phenotype.
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Schizophrenia -- Genetic aspects.
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Genetic markers.
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PSYCHOLOGY -- Psychopathology -- Schizophrenia.
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Phenotype.
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Schizophrenia -- Genetic aspects.
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| Form |
Electronic book
|
| Author |
McDonald, Colm.
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| ISBN |
0203885252 |
|
1135430098 |
|
9780203885253 |
|
9781135430092 |
|
